期刊论文详细信息
Radiation Oncology
Modern radiation therapy and potential fertility preservation strategies in patients with cervical cancer undergoing chemoradiation
Simone Marnitz2  Andreas Jantke1  Christhardt Köhler1  Volker Budach2  Pirus Ghadjar2 
[1] Department of Gynecology, Charité Universitätsmedizin Berlin, Berlin, Germany;Department of Radiation Oncology, Charité Universitätsmedizin Berlin, Augustenburger Platz 1, Berlin, 13353, Germany
关键词: Chemotherapy;    Fertility preservation;    Radiation therapy;    Cervical cancer;   
Others  :  1139719
DOI  :  10.1186/s13014-015-0353-4
 received in 2014-09-16, accepted in 2015-02-05,  发布年份 2015
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【 摘 要 】

Young patients with cervical cancer who undergo chemoradiation might be interested in fertility preservation, not only dependent upon the use of a gestational carrier as maybe achieved by the use of ovarian transposition and cryo-conservation of oocytes or ovarian tissue, but may prefer to carry pregnancy to term after cancer treatment. The latter approach is a non-established concept needing both modern radiation therapy approaches as well as modifications -if at all possible- in current recommendations for target volume delineation to spare dose to the unaffected uterus. Future strategies to serve selected patients in this respect should only be conducted in prospective clinical evaluations and are critically discussed in this article.

【 授权许可】

   
2015 Ghadjar et al.; licensee BioMed Central.

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