Diagnostic workup for endometrioid borderline ovarian tumors (eBOT) requires histopathological evaluation of the uterus

Journal of Ovarian Research

Fabian Trillsch¹  Juliane Reichenbach¹  Sven Mahner¹  Elisa Schmoeckel² 

[1] Department of Obstetrics and Gynecology, University Hospital, Ludwig-Maximilian-University of Munich, Marchioninistrasse 15, 81377, Munich, Germany;Department of Pathology, Ludwig-Maximilian-University of Munich, Thalkirchner Strasse 36, 80337, Munich, Germany;

关键词: Endometrioid borderline ovarian tumor;    Uterine curettage;    Fertility preservation;    Endometrial disorders;    Ovarian metastases;    Endometrial cancer;    Cervical cancer;    Reproductive oncology;    Fertility-sparing surgery;   

DOI  :  10.1186/s13048-021-00839-4

来源: Springer

【 摘 要 】

BackgroundFor young borderline ovarian tumor (BOT) patients, preservation of the uterus was incorporated as an accepted option into treatment guidelines. For the endometrioid subtype (eBOT) however, adequate histological evaluation is challenging and might be associated with synchronous endometrial disorders or misinterpreted as spread from uterine primaries.Case presentationWe report the cases of two young patients with eBOT who underwent treatment according to current guidelines. In both cases, unexpected findings of invasive uterine carcinomas were established in final histopathological evaluation.ConclusionsThis constellation highlights the challenging diagnostic workup of BOT and underlines that uterine curettage is indispensable for eBOT to exclude uterine primary tumors when fertility preservation is planned. Accordingly, we suggest to include this procedure into recommendations for diagnostic workup and to state the potential risk in treatment guidelines.

【 授权许可】

CC BY