期刊论文详细信息
World Journal of Surgical Oncology
FDG PET/CT and MR imaging of intramuscular myxoma in the gluteus maximus
Masatoshi Naito1  Jun Nishio1 
[1] Department of Orthopaedic Surgery, Faculty of Medicine, Fukuoka University, 7-45-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan
关键词: PET/CT;    MRI;    Intramuscular myxoma;    FDG;   
Others  :  827594
DOI  :  10.1186/1477-7819-10-132
 received in 2012-03-11, accepted in 2012-03-11,  发布年份 2012
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【 摘 要 】

Intramuscular myxoma is a rare benign soft tissue tumor which may be mistaken for other benign and low-grade malignant myxoid neoplasms. We present the case of a 63-year-old woman with an asymptomatic intramuscular myxoma discovered incidentally on a whole-body F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography. PET images showed a mild FDG uptake (maximum standardized uptake value, 1.78) in the left gluteus maximus. Subsequent magnetic resonance (MR) imaging revealed a well-defined ovoid mass with homogenous low signal intensity on T1-weighted sequences and markedly high signal intensity on T2-weighted sequences. Contrast-enhanced MR images showed heterogeneous enhancement throughout the mass. The diagnosis of intramuscular myxoma was confirmed on histopathology after surgical excision of the tumor. The patient had no local recurrence at one year follow-up. Our case suggests that intramuscular myxoma should be considered in the differential diagnosis of an oval-shaped intramuscular soft tissue mass with a mild FDG uptake.

【 授权许可】

   
2012 Nishio and Naito; licensee BioMed Central Ltd.

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【 参考文献 】
  • [1]Zoccali C, Teori G, Prencipe U, Erba F: Mazabraud’s syndrome: a new case and review of the literature. Int Orthop 2009, 33:605-610.
  • [2]Ho L, Wassef H, Henderson R, Seto J: F-18 fluorodeoxyglucose positron emission tomography/computed tomography imaging in left thigh intramuscular myxoma. Clin Nucl Med 2009, 34:224-225.
  • [3]Nielsen GP, O’Connell JX, Rosenberg AE: Intramuscular myxoma: a clinicopathologic study of 51 cases with emphasis on hypercellular and hypervascular variants. Am J Surg Pathol 1998, 22:1222-1227.
  • [4]Murphey MD, McRae GA, Fanburg-Smith JC, Levine AM, Aboulafia AJ: Imaging of soft-tissue myxoma with emphasis on CT and MR and comparison of radiologic and pathologic findings. Radiology 2002, 225:215-224.
  • [5]Silver WP, Harrelson JM, Scully SP: Intramuscular myxoma: a clinicopathologic study of 17 patients. Clin Orthop Relat Res 2002, 403:191-197.
  • [6]Okamoto S, Hisaoka M, Ushijima M, Nakahara S, Toyoshima S, Hashimoto H: Activating Gs(alpha) mutation in intramuscular myxomas with and without fibrous dysplasia of bone. Virchows Arch 2000, 437:133-137.
  • [7]Delaney D, Diss TC, Presneau N, Hing S, Berisha F, Idowu BD, O’Donnell P, Skinner JA, Tirabosco R, Flanagan AM: GNAS1 mutations occur more commonly than previously thought in intramuscular myxoma. Mod Pathol 2009, 22:718-724.
  • [8]Willems SM, Mohseny AB, Balog C, Sewrajsing R, Briaire-de Bruijn IH, Knijnenburg J, Cleton-Jansen AM, Sciot R, Fletcher CD, Deelder AM, Szuhai K, Hensbergen PJ, Hogendoorn PC: Cellular/intramuscular myxoma and grade I myxofibrosarcoma are characterized by distinct genetic alterations and specific composition of their extracellular matrix. J Cell Mol Med 2009, 13:1291-1301.
  • [9]Nishio J, Iwasaki H, Nabeshima K, Naito M: Cytogenetics and molecular genetics of myxoid soft tissue sarcomas. Genetics Research International 2011, 2011:497148.
  • [10]Bancroft LW, Kransdorf MJ, Menke DM, O’Connor MI, Foster WC: Intramuscular myxoma: characteristic MR imaging features. AJR Am J Roentgenol 2002, 178:1255-1259.
  • [11]Nishimoto K, Kusuzaki K, Matsumine A, Seto M, Fukutome K, Maeda M, Hosoi S, Uchida A: Surrounding muscle edema detected by MRI is valuable for diagnosis of intramuscular myxoma. Oncol Rep 2004, 11:143-148.
  • [12]Luna A, Martinez S, Bossen E: Magnetic resonance imaging of intramuscular myxoma with histological comparison and a review of the literature. Skeletal Radiol 2005, 34:19-28.
  • [13]Singnurkar A, Phancao JP, Chatha DS, Stern J: The appearance of Mazabraud’s syndrome on 18 F-FDG PET/CT. Skeletal Radiol 2007, 36:1085-1089.
  • [14]Suzuki R, Watanabe H, Yanagawa T, Sato J, Shinozaki T, Suzuki H, Endo K, Takagishi K: PET evaluation of fatty tumors in the extremity: possibility of using the standardized uptake value (SUV) to differentiate benign tumors from liposarcoma. Ann Nucl Med 2005, 19:661-670.
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