A small pancreatic hamartoma with an obstruction of the main pancreatic duct and avid FDG uptake mimicking a malignant pancreatic tumor: a systematic case review

BMC Gastroenterology

Case Report

Takashi Yoshiura¹  Yoshihiko Fukukura¹  Mari Toyota²  Toru Niihara²  Sadao Tanaka³  Masayuki Nakajo⁴  Hiroaki Nagano⁴  Yoriko Kajiya⁴  Atsushi Tani⁴  Masaki Kitazono⁵  Toyokuni Suenaga⁵ 

[1] Department of Radiology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, 890-8544, Kagoshima-shi, Kagoshima, Japan;Departments of Gastroenterology, Nanpuh Hospital, 14-3 Nagata, 892-8512, Kagoshima, Japan;Departments of Pathology, Nanpuh Hospital, 14-3 Nagata, 892-8512, Kagoshima, Japan;Departments of Radiology, Nanpuh Hospital, 14-3 Nagata, 892-8512, Kagoshima, Japan;Departments of Surgery, Nanpuh Hospital, 14-3 Nagata, 892-8512, Kagoshima, Japan;

关键词: Hamartoma;    Pancreas;    CT;    MRI;    FDG;    PET/CT;   

DOI  :  10.1186/s12876-017-0704-8

 received in 2016-07-05, accepted in 2017-11-24,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundPancreatic hamartomas are extremely rare and may be misdiagnosed as malignant tumors. We report herein a case of a small, solid-type pancreatic hamartoma.Case presentationA 72-year-old female was incidentally detected pancreatic lesion by ultrasonography. Computed tomography and magnetic resonance imaging revealed a 2.0-cm solid lesion. The main pancreatic duct (MPD) was obstructed by the lesion in the head of the pancreas, and the upstream MPD was dilated. 18F-fluorodeoxyglucose (FDG) accumulated avidly in the lesion and increased in FDG intensity from the early to the delayed images. The histopathological studies confirmed the diagnosis of pancreatic hamartoma. Immunohistochemically, the cell membrane of the accessory glands and ducts showed homogeneous expression of glucose transporter type I and hexokinase II.ConclusionPancreatic hamartomas causing dilatation of the MPD are extremely rare, and this appears to be the first case of a hamartoma to take up FDG avidly. It was a rare occurrence and should be noted that pancreatic hamartomas can cause an obstruction of the MPD and show avid FDG uptake, thereby mimicking malignant pancreatic tumors.

【 授权许可】

CC BY   
© The Author(s). 2017