A multidisciplinary approach for peritoneal carcinomatosis and bilobar liver metastases from colorectal cancer: case report and review of the literature

World Journal of Surgical Oncology

José A. Pérez-Daga¹  Francisco J. Moreno-Ruiz¹  César P. Ramírez-Plaza¹ 

[1] General and Digestive Surgery Service, Hospital Quirón, Avenida Imperio Argentina 1, Malaga, 29004, Spain

关键词: Hyperthermia;    Intraperitoneal chemotherapy;    Cytoreductive surgery;    Colorectal cancer;    Peritoneal carcinomatosis;    Liver metastases;   

Others  :  1223992
DOI  :  10.1186/s12957-015-0654-y

 received in 2015-04-15, accepted in 2015-07-20,  发布年份 2015

【 摘 要 】

Background

Peritoneal carcinomatosis develops in 15 % of patients with primary colorectal cancer (CRC) and in 25 % of those with recurrence. Liver metastases are also frequent and appear at some time in 35–55 % of patients with CRC. When both conditions are present and treated palliatively, the expected median survival is 5–6 months. Recent publications suggest survival is improved when R0 resection of both peritoneal and liver diseases is achieved.

Case presentation

A 36-year-old woman with synchronous peritoneal and liver metastases of colorectal origin was treated with a stepwise approach consisting of initial cytoreductive surgery, minor liver resection, intraperitoneal intraoperative hyperthermic chemotherapy, adjuvant chemotherapy, right portal embolization, and finally, right hepatectomy achieving an R0 resection. The patient is alive and free of disease after 30 months of follow-up.

Discussion

Patients with peritoneal carcinomatosis and liver metastases from CRC must be carefully evaluated by multidisciplinary oncological teams in order to offer the possibility of surgery to obtain an R0 resection in selected patients (especially if the peritoneal cancer index is <19 and there is resectable or potentially resectable metastatic liver disease).

【 授权许可】

   
2015 Ramírez-Plaza et al.

【 图 表 】

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