Particle and Fibre Toxicology | |
Efficacy of a proprietary formulation of fipronil/(S)-methoprene/cyphenothrin against Ixodes scapularis tick infestations on dogs | |
Ruchika Solanki2  Sheila J. Gross3  William Russell Everett1  Doug Carithers2  | |
[1] BerTek, Inc., Greenbrier, AR, USA;Merial, Inc., 3239 Satellite Blvd, Duluth 30096, GA, USA;Independent Contract Statistician, Piscataway, NJ, USA | |
关键词: Tick control; Efficacy; Dogs; Deer tick; Ixodes scapularis; | |
Others : 1222205 DOI : 10.1186/s13071-015-0992-1 |
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received in 2015-05-15, accepted in 2015-07-08, 发布年份 2015 | |
【 摘 要 】
Background
Efficacy of FRONTLINE® TRITAK® For Dogs (fipronil/(S)-methoprene/cyphenothrin, Merial, Inc., Duluth, GA) against Ixodes scapularis was evaluated in two separate, but concurrent laboratory studies.
Methods
One day after topical treatment with placebo or active, dogs (n = 24) were infested with 50 unfed adult Ixodes scapularis ticks, with repeat infestations on Days 7, 14, 21 and 28. The number of live ticks was counted at 6 hours post-infestation in the first study (n = 12) and at 24 hours post-infestation in the second study (n = 12).
Results
Observed efficacies in study 1 were 93-99 % at 6 hour assessments on Day 1 through Day 28 and in the second study, 98-100 % at 24 hour assessments, occurring on Day 2 through Day 29.
Conclusions
A single dose of FRONTLINE® TRITAK® For Dogs (fipronil/(S)-methoprene/cyphenothrin) (0.67 ml or 1.34 ml) prevented the establishment of a new infestation following treatment, as well as the repeated weekly re-infestations with Ixodes scapularis ticks, for 4 weeks.
【 授权许可】
2015 Carithers et al.
【 预 览 】
Files | Size | Format | View |
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20150805113153952.pdf | 381KB | download |
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