Highly aggressive pathology of non-functional parathyroid carcinoma

Orphanet Journal of Rare Diseases

Rares Buiga¹  Andra Piciu³  George Kontogeorgos²  Alexandru Irimie⁴  Doina Piciu⁴ 

[1] Department of Pathology, Ion Chiricuţă Institute of Oncology, Cluj-Napoca 400015, România;Department of Pathology Athens, G. Gennimatas General Hospital, Athens, Greece;Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca 400023, România;Department of Oncology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca 400023, România

关键词: Non-functional;    Cancer;    Parathyroid;   

Others  :  863628
DOI  :  10.1186/1750-1172-8-115

 received in 2013-05-23, accepted in 2013-08-01,  发布年份 2013

【 摘 要 】

Parathyroid carcinoma is a rare malignant endocrine tumor accounting for only 0.5% to 5% of all primary hyperparathyroidism. Among these malignancies, only 10-25% are nonfunctioning. After the review of the literature we could only ascertain a number of 25 cases reported worldwide, since 1929, our case being the 26th, but the first with a very aggressive pathology, treated with chemotherapy scheme usually used for neuroendocrine tumors. Considering these facts, every single case presented is a step forward in defying the clinical presentation, for the awareness of the clinicians, and also in establishing standard adjuvant therapies.

【 授权许可】

   
2013 Piciu et al.; licensee BioMed Central Ltd.

【 图 表 】

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