Concept for individualized patient allocation: ReCompare—remote comparison of particle and photon treatment plans

Radiation Oncology

Michael Baumann⁵  Wolfgang Enghardt⁵  Mechthild Krause⁵  Uwe Just¹  Jørgen B Petersen⁴  Annika Jakobi³  Stephan Helmbrecht³  Klaus Roth³  Steffen Löck³  Armin Lühr² 

[1] Department of Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307 Dresden, Germany;German Cancer Consortium (DKTK), Dresden, Germany and German Cancer Research Center (DKFZ), Heidelberg, Germany;OncoRay—National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, PF 41, 01307 Dresden, Germany;Department of Medical Physics, Aarhus University Hospital, Aarhus, Denmark;Institute of Radiation Oncology, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany

关键词: Treatment plan comparison;    Particle therapy, Patient selection;    Proton therapy;   

Others  :  813975
DOI  :  10.1186/1748-717X-9-59

 received in 2013-11-21, accepted in 2014-02-13,  发布年份 2014

【 摘 要 】

Background

Identifying those patients who have a higher chance to be cured with fewer side effects by particle beam therapy than by state-of-the-art photon therapy is essential to guarantee a fair and sufficient access to specialized radiotherapy. The individualized identification requires initiatives by particle as well as non-particle radiotherapy centers to form networks, to establish procedures for the decision process, and to implement means for the remote exchange of relevant patient information. In this work, we want to contribute a practical concept that addresses these requirements.

Methods

We proposed a concept for individualized patient allocation to photon or particle beam therapy at a non-particle radiotherapy institution that bases on remote treatment plan comparison. We translated this concept into the web-based software tool ReCompare (REmote COMparison of PARticlE and photon treatment plans).

Results

We substantiated the feasibility of the proposed concept by demonstrating remote exchange of treatment plans between radiotherapy institutions and the direct comparison of photon and particle treatment plans in photon treatment planning systems. ReCompare worked with several tested standard treatment planning systems, ensured patient data protection, and integrated in the clinical workflow.

Conclusions

Our concept supports non-particle radiotherapy institutions with the patient-specific treatment decision on the optimal irradiation modality by providing expertise from a particle therapy center. The software tool ReCompare may help to improve and standardize this personalized treatment decision. It will be available from our website when proton therapy is operational at our facility.

【 授权许可】

   
2014 Lühr et al.; licensee BioMed Central Ltd.

【 图 表 】

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