Age-period cohort analysis of AIDS incidence rates in Rio de Janeiro, Brazil, 1985–2009

Population Health Metrics

Cristina Pinheiro Nádia Rodrigues¹ 

[1] Departamento de Tecnologias da Informação e Educação em Saúde/ Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, Brazil

关键词: Epidemiology;    Period effect;    Cohort effect;    Age effect;    Sexually transmitted diseases;    Acquired immunodeficiency syndrome;   

Others  :  1139737
DOI  :  10.1186/1478-7954-11-22

 received in 2012-06-10, accepted in 2013-11-18,  发布年份 2013

【 摘 要 】

Introduction

The long average incubation time from HIV infection to AIDS makes it difficult to estimate the recent tendencies of HIV from AIDS incidence data. The objective of this study was to investigate the effects of three temporal components in AIDS incidence in the state of Rio de Janeiro, Brazil - age, period, and cohort.

Methods

Age-specific AIDS incidence rates per 100,000 from Rio de Janeiro (Brazil) were calculated for both sexes using five-year age classes from 1985 to 2009 based on reported data from the Notifiable Disease Information System of the Brazilian Ministry of Health and from census population counts. Multivariate negative binomial models were used to analyze the risk of AIDS by age, period, and birth cohort.

Results

From 1985 to 2009, AIDS incidence initially increased with age in each birth cohort and then decreased (except for individuals born from 1971–1979 to 1986–1994). High peaks in the rates in each birth cohort were detected in 1995–1999 for males and in 2000–2004 for females. Multivariate analysis showed the maximum risk of AIDS in the 30–34 age group and 1958–1962 birth cohort.

Conclusion

Age, birth cohort, and period effects all may have influenced the AIDS incidence rates over the period investigated. From 1985 to 1999, comparison of the tendencies (by age) of the period with the birth cohort revealed opposing tendencies in individuals older than 29 years and in the youngest age groups (0 to 14 years). From 2000 to 2009, a strong age effect can be observed in both sexes. Consistent changes in period tendency curves suggest the occurrence of period effects. A reduction in the intensity of the risk of AIDS can be observed after 2000–2004.

【 授权许可】

   
2013 Rodrigues; licensee BioMed Central Ltd.

【 图 表 】

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