Incidence and mortality rates of lip, oral cavity, and pharynx cancers in Brazil: time-trend and age-period-cohort analysis from the last 30 years, Global Burden of Disease Study

Sociedade Brasileira de Medicina Tropical. Revista

article

Romagna, Daniel Volpato¹  Oliveira, Max Moura de²  Abreu, Lucas Guimarães³  Stein, Caroline⁴  Hugo, Fernando Neves⁴  Teixeira, Renato³  Malta, Deborah Carvalho³  Naghavi, Mohsen⁵  Iser, Betine Pinto Moehlecke¹ 

[1] Universidade do Sul de Santa Catarina;Universidade Federal de Goiás;Universidade Federal de Minas Gerais;Universidade Federal do Rio Grande do Sul;University of Washington

关键词: Head and neck câncer;    Epidemiology;    Incidence;    Mortality;    Cohort effect;    Global Burden of Disease;   

DOI  :  10.1590/0037-8682-0286-2021

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

INTRODUCTION:Cancers are the second main cause of morbidity worldwide, but robust information on lip, oral cavity, and pharynx cancers in Brazil is lacking. This study aimed to analyze the trends of incidence and mortality caused by lip, oral cavity, and pharynx cancers and age-period-cohort effects in the Brazilian population of 30 years of age and over, in the period of 1990 to 2019.METHODS:A time series study of the incidence and mortality rates for oral cavity and pharynx cancer (“Lip and oral cavity cancer”, “Nasopharynx cancer”, and “Other pharynx cancer”) was conducted, with corrected data from the Global Burden of Disease Study (GBD) 2019. Age-standardized rates per 100,000 inhabitants, for the global population, were gathered according to the individuals’ sex. The annual average percentage change (AAPC) was estimated, as was the age-period-cohort effects. RESULTS: The incidence and mortality rates were higher for men in the studied anatomical regions. The cancers tended to decrease for men, except for nasopharynx cancer, which increased in individuals of both sexes. Mortality tended to present a decline in most of the groups studied. For men and women, the age-period-cohort model presented a better adjustment for both incidence and mortality. CONCLUSIONS:Incidence and mortality caused by the main head and neck cancers showed a tendency to decline over the past 30 years in Brazil, except for nasopharynx cancer, which showed an increase in incidence and mortality in some segments of the population. Higher rates were found for lip and oral cavity cancers in men.

【 授权许可】

CC BY