Target splitting non-coplanar RapidArc radiation therapy for a diffuse sebaceous carcinoma of the scalp: a novel delivery technique

Radiation Oncology

ZhenYu Qi¹  ALong Chen¹  DeHua Kang¹  ZhiChun He¹  WeiWei Xiao¹  Jiang Hu¹ 

[1] Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China

关键词: Dosimetry;    Non-coplanar;    Target splitting;    RapidArc;    Total scalp irradiation;   

Others  :  1151372
DOI  :  10.1186/1748-717X-9-204

 received in 2013-11-10, accepted in 2014-08-28,  发布年份 2014

【 摘 要 】

Background and purpose

To compare conventional lateral photon-electron, fixed-beam intensity modulated radiation therapy (IMRT), coplanar and non-coplanar RapidArc for the treatment of a diffuse sebaceous gland carcinoma of the scalp.

Methods

Comprehensive dosimetry comparisons were performed among 3D-CRT, IMRT and various RapidArc plans. Target coverage, conformity index (CI), homogeneity index (HI) and doses to organs at risk (OAR) were calculated. Monitor unites (MUs) and delivery time of each treatment were also recorded to evaluate the execution efficiency. The influence of target splitting technique and non-coplanar planning on plan quality was discussed.

Results

IMRT was superior to 3D-CRT concerning targets’ coverage at the sacrifice of larger irradiated brain volumes to low doses. CIs and HIs were better in coplanar RapidArc and non-coplanar RapidArc plans than 3D-CRT and IMRT. Best dose coverage and sparing of OARs were achieved in non-coplanar plans using target splitting technique. Treatment delivery time was longest in the IMRT plan and shortest in the coplanar RapidArc plan without target splitting. The 3%/3 mm gamma test pass rates were above 95% for all the plans.

Conclusions

Target splitting technique and non-coplanar arcs are recommended for total scalp irradiation.

【 授权许可】

   
2014 Hu et al.; licensee BioMed Central Ltd.

【 图 表 】

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