Retrospective analysis of individual risk factors for urethrocutaneous fistula after onlay hypospadias repair in pediatric patients

Italian Journal of Pediatrics

Yun-Fei Guo¹  Xiao-Jiang Zhu¹  Hao-Bo Zhu¹  Chen-Jun Chen¹  Li-Xia Wang¹  Yong-Ji Deng¹  Ru-Gang Lu¹  Geng Ma¹  Jun Tian²  Zheng Ge¹  Li-Qu Huang¹ 

[1] Department of Urology, Nanjing Children’s Hospital Affiliated to Nanjing Medical University, Nanjing 210008, Jiangsu, China;Department of Urology, Beijing Children’s Hospital Affiliated Hospital of Capital Medical University, Beijing 100045, China

关键词: Onlay island flap;    Risk factors;    Urethrocutaneous fistula;    Hypospadias;   

Others  :  1180743
DOI  :  10.1186/s13052-015-0140-8

 received in 2015-01-08, accepted in 2015-04-13,  发布年份 2015

【 摘 要 】

Background

To retrospectively identify the individual risk factors for the urethrocutaneous fistula (UCF) in pediatric patients after hypospadias repair (HR) with onlay island flap urethroplasty.

Methods

A total of 167 patients who underwent primary HR at Nanjing Medical University Affiliated Children Hospital from January 2009 to December 2012 were enrolled. Clinical data including the patient’ age at HR, hypospadias type and urethral defect length were documented.

Results

Among 167 patients, 12.6% patients (n = 21) developed UCF after HR. Postoperative UCF occurred in 3.9% (3/76) cases at age of 0–2 years, 14.3% (9/63) at 2–4 years, 20.0% (2/10) at 4–6 years and 38.9% (7/18) at 6–12 years. The incidences of UCF were 12.0% (3/25), 11.4% (5/132) and 30.0% (3/10) for distal, middle and proximal types of hypospadias. As to the urethral defect length, the incidences of UCF were 8.2% (5/61) in patients with a length of ≤ 2 cm, 12.8% (9/70) in 2-3 cm, 22.6% (7/31) in 3–4 cm and 0% (0/5) in above 4 cm. Older age at HR was significantly associated with the high incidence of UCF formation (P = 0.004), while the hypospadias type and urethral defect length did not affect it (P = 0.264 and P = 0.312, respectively).

Conclusions

The patient’ age at HR was a risk factor for the UCF formation after HR, and treatment of HR within two years old might be with the least incidence of UCF.

【 授权许可】

   
2015 Huang et al.; licensee BioMed Central.

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