期刊论文详细信息
Journal of Medical Case Reports
A 35-year-old woman presenting with an unusual post-traumatic leiomyoma of the nipple: a case report
Efterpi Demiri1  Dimitris Dionyssiou1  Manousos Georgios Pramateftakis3  Georgia-Alexandra Spyropoulou1  Efstratios Vakirlis2  Leonidas Pavlidis1 
[1] Plastic Surgery Department, Aristotle University of Thessaloniki, Papageorgiou Hospital Thessaloniki, Thessaloniki, Greece;First Department of Dermatology and Venereology, Aristotle University of Thessaloniki, Delfon 124, Thessaloniki, Greece;Department of Surgery, European Interbalkan Medical Center, Asklipiou 10, Pylaia, Thessaloniki, Greece
关键词: Leiomyoma;    Nipple;    Benign tumors;   
Others  :  1181270
DOI  :  10.1186/1752-1947-7-49
 received in 2012-09-27, accepted in 2013-01-15,  发布年份 2013
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【 摘 要 】

Introduction

Leiomyoma of the mammary papilla is one of the most uncommon nipple tumors with only 50 cases reported in the literature until now. To the best of our knowledge we present the first report of a nipple leiomyoma that originated from a traumatic abrasion caused by breastfeeding.

Case presentation

A 35-year-old healthy Caucasian female with a cauliflower-like tender and pink nodular mass that was approximately 10mm in diameter presented to our out-patients department. The patient suggested that the mass originated from a traumatic abrasion caused by breastfeeding three years ago and it has been slowly growing ever since.

An excision biopsy was performed. The histological and immunohistochemical examination confirmed the diagnosis of leiomyoma. There were no postoperative complications or any sign of local recurrence four years postoperatively.

Conclusions

Leiomyoma of the mammary papilla is a rare benign neoplasm that usually appears as a solid tender nodule. Differential diagnosis comprises breast carcinoma, leiomyosarcoma and myoid hamartoma. The recommended treatment is complete excision of the tumor with histologically confirmed tumor-free margins otherwise recurrence is possible. A detailed history of the patient’s disease can reveal the original etiology. This is an original case report that will have particular interest to plastic surgeons, dermatologists, and pathologists. The pathogenetic mechanism was trauma of the nipple. According to our review of the literature this particular information has never been reported and we think that it may advance our knowledge of this very infrequent tumor.

【 授权许可】

   
2013 Pavlidis et al; licensee BioMed Central Ltd.

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【 参考文献 】
  • [1]Nakamura S, Hashimoto Y, Takeda K, Nishi K, Ishida-Yamamoto A, Mizumoto T, Lizuka H: Two cases of male nipple leiomyoma: idiopathic leiomyoma and gynecomastia-associated leiomyoma. Am J Dermatopathol 2012, 34(3):287-291.
  • [2]Kaufman HL, Hirsch EF: Leiomyoma of the breast. J Surg Oncol 1996, 62:62-64.
  • [3]Nascimento AG, Karas M, Rosen PP, Caron AG: Leiomyoma of the Nipple. Am J Surg Pathol 1979, 3(2):151-154.
  • [4]Diaz-Arias AA, Hurt MA, Loy TS, Seeger RM, Bickel JT: Leiomyoma of the breast. HumPathol 1989, 20:396-399.
  • [5]Bulman JFH: Leiomyoma of Nipple. Br Med J 1951, 2(4737):975.
  • [6]Virchow R: Uber cavernose (erektile) Geschwulste und Teleangiektasien. Virchows Arch Pathol Anat 1854, 6:525-554.
  • [7]Son EJ, Oh KK, Kim EK, Son HJ, Jung WH, Lee HD: Leiomyoma of the breast in a 50-year-old woman receiving tamoxifen. AJR Am J Roentgenol 1998, 171(6):1684-1686.
  • [8]Sidoni A, Luthy M, Belezza G, Consiglio MA, Bucciarelli E: Leiomyoma of the breast: case report and review of the literature. Breast 1999, 8(5):289-290.
  • [9]Haier J, Haensh W, Schon M: Leiomyoma as a rare differential diagnosis of Paget’s disease of the nipple. Acta Obstet Gynecol Scand 1997, 76:490-491.
  • [10]Pujol RM, Fernandez MT: A solitary papule on the nipple. Arch Dermatol 1991, 127:571-576.
  • [11]Ku J, Campbell C, Bennett I: Leiomyoma of the nipple. Breast J 2006, 12(4):377-380.
  • [12]Christenson LJ, Smith K, Arpey CJ: Treatment of multiple cutaneous leiomyomas with CO2 laser ablation. Dermatol Surg 2000, 26:319-322.
  • [13]Joseph KA, Shutter J, Tamer M, Schnabel F: Cutaneous subareolar leiomyoma. A rare clinical entity. Breast J 2005, 11(6):501-502.
  • [14]Chaudhary KS, Shousha S: Leiomyoma of the nipple, and normal subareolar muscle fibres, are oestrogen and progesterone receptor positive. Histopathology 2004, 44:626-628.
  • [15]Hernandez FJ: Leiomyosarcoma of male breast originating in the nipple. Am J Surg Pathol 1978, 3:299-304.
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