Metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis

Clinical Sarcoma Research

A P Dei Tos¹  D Vanel³  D Donati²  T Frisoni²  M Sbaraglia¹  M Gambarotti³  A Righi³ 

[1] Department of Pathology, Treviso Regional Hospital, Treviso, Italy;Oncologic Department, Rizzoli Orthopaedic Institute, Bologna, Italy;Department of Pathology, Istituto Ortopedico Rizzoli, Via del Barbiano 1/10, Bologna, 40136, Italy

关键词: Metastases;    Lymph node;    Diffuse type;    Tenosynovial giant cell tumor;   

Others  :  1217304
DOI  :  10.1186/s13569-015-0030-2

 received in 2015-05-06, accepted in 2015-05-21,  发布年份 2015

【 摘 要 】

Tenosynovial giant cell tumour, diffuse type, also known under a variety of other terms including diffuse pigmented villonodular synovitis, tends to be locally aggressive and not infrequently can show multiple recurrences. The differential diagnosis with the extremely rare and somewhat controversial malignant variant of tenosynovial giant cell tumour, diffuse type, is challenging due to overlapping radiologic features of these two entities. Malignant tenosynovial giant cell tumour is defined by the presence of overtly malignant sarcomatous areas. We describe a very unusual case of a 63-year-old man affected by tenosynovial giant cell tumour, diffuse type of the knee that, despite absence of morphologic evidence of sarcomatous transformation, developed inguinal lymph node metastases following multiple surgical procedures.

【 授权许可】

   
2015 Righi et al.

【 图 表 】

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