期刊论文详细信息
Extreme Physiology & Medicine
Frostbite: a practical approach to hospital management
Christopher HE Imray3  Amalia Cochran8  Luanne Freer4  Scott E McIntosh1  Caitlin EA Imray7  Katie Russell6  Pauline Buxton2  Charles Handford5 
[1] Division of Emergency Medicine, University of Utah Health Care, Salt Lake City, UT 84112, USA;University Hospital Coventry & Warwickshire, Coventry CV2 2DX, UK;Warwick Medical School, The University of Warwick, Coventry CV4 7AL, UK;Everest ER, Himalayan Rescue Association, P.O. Box 4944, Kathmandu 44601, Nepal;Queen Elizabeth Hospital, Birmingham B15 2TH, UK;University of Utah, Salt Lake City, UT 84112, USA;Sheffield University Medical School, Sheffield S10 2TN, UK;University of Utah School of Medicine, Salt Lake City, UT 84132, USA
关键词: Iloprost;    TPA;    Heparin;    Thrombolysis;    Rewarming;    Hypothermia;    Frostbite;   
Others  :  802242
DOI  :  10.1186/2046-7648-3-7
 received in 2013-11-20, accepted in 2014-02-24,  发布年份 2014
PDF
【 摘 要 】

Frostbite presentation to hospital is relatively infrequent, and the optimal management of the more severely injured patient requires a multidisciplinary integration of specialist care. Clinicians with an interest in wilderness medicine/freezing cold injury have the awareness of specific potential interventions but may lack the skill or experience to implement the knowledge. The on-call specialist clinician (vascular, general surgery, orthopaedic, plastic surgeon or interventional radiologist), who is likely to receive these patients, may have the skill and knowledge to administer potentially limb-saving intervention but may be unaware of the available treatment options for frostbite. Over the last 10 years, frostbite management has improved with clear guidelines and management protocols available for both the medically trained and winter sports enthusiasts. Many specialist surgeons are unaware that patients with severe frostbite injuries presenting within 24 h of the injury may be good candidates for treatment with either TPA or iloprost. In this review, we aim to give a brief overview of field frostbite care and a practical guide to the hospital management of frostbite with a stepwise approach to thrombolysis and prostacyclin administration for clinicians.

【 授权许可】

   
2014 Handford et al.; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20140708021147485.pdf 1477KB PDF download
Figure 3. 287KB Image download
Figure 2. 89KB Image download
Figure 1. 63KB Image download
【 图 表 】

Figure 1.

Figure 2.

Figure 3.

【 参考文献 】
  • [1]Gross EA, Moore JC: Using thrombolytics in frostbite injury. J Emerg Trauma Shock 2012, 5(3):267-271.
  • [2]Post PW, Donner DD: Frostbite in a pre-Columbian mummy. Am J Phys Anthropol 1972, 37(2):187-191.
  • [3]Larrey DJ, Hall RW: Memoirs of Military Surgery. Joseph Cushing: Baltimore; 1814. [1st American edition from the 2nd Paris edition]
  • [4]Hallam MJ, Cubison T, Dheansa B, Imray C: Managing frostbite. BMJ 2010, 341:c5864.
  • [5]Murphy JV, Banwell PE, Roberts AH, McGrouther DA: Frostbite: pathogenesis and treatment. J Trauma 2000, 48(1):171-178.
  • [6]Sever C, Kulahci Y, Acar A, Karabacak E: Unusual hand frostbite caused by refrigerant liquids and gases (Ulusal travma ve acil cerrahi dergisi). TJTES 2010, 16(5):433-438.
  • [7]Wegener EE, Barraza KR, Das SK: Severe frostbite caused by Freon gas. South Med J 1991, 84(9):1143-1146.
  • [8]Ikaheimo TM, Hassi J: Frostbites in circumpolar areas. Global Health Action 2011., 4doi:10.3402/gha.v4i0.8456. Epub 2011 Oct 10
  • [9]Valnicek SM, Chasmar LR, Clapson JB: Frostbite in the prairies: a 12-year review. Plast Reconstr Surg 1993, 92(4):633-641.
  • [10]Reamy BV: Frostbite: review and current concepts. J Am Board Fam Pract 1998, 11(1):34-40.
  • [11]Imray C, Grieve A, Dhillon S, Caudwell Xtreme Everest Research Group: Cold damage to the extremities: frostbite and non-freezing cold injuries. Postgrad Med J 2009, 85(1007):481-488.
  • [12]Guyatt G, Gutterman D, Baumann MH, Addrizzo-Harris D, Hylek EM, Phillips B, Raskob G, Lewis SZ, Schünemann H: Grading strength of recommendations and quality of evidence in clinical guidelines: report from an American College of Chest Physicians Task Force. Chest 2006, 129(1):174-181.
  • [13]Syme D, ICAR Medical Commission: Position paper: on-site treatment of frostbite for mountaineers. High Alt Med Biol 2002, 3(3):297-298.
  • [14]McIntosh SE, Hamonko M, Freer L, Grissom CK, Auerbach PS, Rodway GW, Cochran A, Giesbrecht G, McDevitt M, Imray CH, Johnson E, Dow J, Hackett PH, Wilderness Medical Society: Wilderness Medical Society practice guidelines for the prevention and treatment of frostbite. Wild Environ Med 2011, 22(2):156-166.
  • [15]Murkowski FH, Mandsager R, Choromanski Hull-Jilly D: State of Alaska Cold Injuries Guidelines. Juneau: Department of Health and Social Services of Alaska; 2003:36-41. Revised 01/2005
  • [16]McCauley RL, Hing DN, Robson MC, Heggers JP: Frostbite injuries: a rational approach based on the pathophysiology. J Trauma 1983, 23(2):143-147.
  • [17]Sheridan RL, Goldstein MA, Stoddard FJ Jr, Walker TG: Case records of the Massachusetts General Hospital. Case 41–2009. A 16-year-old boy with hypothermia and frostbite. New Engl J Med 2009, 361(27):2654-2662.
  • [18]Cauchy E, Chetaille E, Marchand V, Marsigny B: Retrospective study of 70 cases of severe frostbite lesions: a proposed new classification scheme. Wilderness Environ Med 2001, 12(4):248-255.
  • [19]Cauchy E, Marsigny B, Allamel G, Verhellen R, Chetaille E: The value of technetium 99 scintigraphy in the prognosis of amputation in severe frostbite injuries of the extremities: a retrospective study of 92 severe frostbite injuries. J Hand Surg 2000, 25(5):969-978.
  • [20]Johnson AR, Jensen HL, Peltier G, DelaCruz E: Efficacy of intravenous tissue plasminogen activator in frostbite patients and presentation of a treatment protocol for frostbite patients. Foot Ankle Spec 2011, 4(6):344-348. doi:10.1177/1938640011422596
  • [21]Barker JR, Haws MJ, Brown RE, Kucan JO, Moore WD: Magnetic resonance imaging of severe frostbite injuries. Ann Plast Surg 1997, 38(3):275-279.
  • [22]Edmonson GR, Bretzman PA, Mohr WJ, Ahernholtz DH: Intra-arterial thrombolytic therapy for limb salvage in severe frostbite. J Vasc Interv Radiol 2008, 19:37.
  • [23]Saemi AM, Johnson JM, Morris CS: Treatment of bilateral hand frostbite using transcatheter arterial thrombolysis after papaverine infusion. Cardiovasc Intervent Radiol 2009, 32:1280-1283.
  • [24]Salimi Z, Wolverson MK, Herbold DR, Vas W, Salimi A: Treatment of frostbite with i.v. streptokinase: an experimental study in rabbits. AJR 1987, 149(4):773-776.
  • [25]Twomey JA, Peltier GL, Zera RT: An open-label study to evaluate the safety and efficacy of tissue plasminogen activator in treatment of severe frostbite. J Trauma 2005, 59(6):1350-1354. Discussion 54–5
  • [26]Bruen KJ, Ballard JR, Morris SE, Cochran A, Edelman LS, Saffle JR: Reduction of the incidence of amputation in frostbite injury with thrombolytic therapy. Arch Surg 2007, 142(6):546-551. Discussion 51–3
  • [27]Roche-Nagle G, Murphy D, Collins A, Sheehan S: Frostbite: management options. Eur J Emerg Med 2008, 15(3):173-175.
  • [28]Groechenig E: Treatment of frostbite with iloprost. Lancet 1994, 344(8930):1152-1153.
  • [29]Cauchy E, Cheguillaume B, Chetaille E: A controlled trial of a prostacyclin and rt-PA in the treatment of severe frostbite. N Engl J Med 2011, 364(2):189-190.
  • [30]Andrew J: Life and Limb. UK: Piatkus; 2005. 320 (New Ed edition, 24 Feb 2005). ISBN-10: 0749950528, ISBN-13: 978-0749950521
  • [31]Mills WJ Jr: Frostbite. A discussion of the problem and a review of the Alaskan experience. Alaska Med 1993, 35:29-40.
  • [32]Poulakidas S, Cologne K, Kowal-Vern A: Treatment of frostbite with subatmospheric pressure therapy. J Burn Care Res 2008, 29(6):1012-1014.
  • [33]Khaira HS, Coddington T, Drew A, Roberts PN, Imray CH: Patellar tendon bearing orthosis–application as adjunctive treatment in healing of lower-limb tissue loss. Eur J Vasc Endovasc Surg 1998, 16(6):485-488.
  • [34]von Heimburg D, Noah EM, Sieckmann UP, Pallua N: Hyperbaric oxygen treatment in deep frostbite of both hands in a boy. Burns 2001, 27(4):404-408.
  • [35]Gage AA, Ishikawa H, Winter PM: Experimental frostbite. The effect of hyperbaric oxygenation on tissue survival. Cryobiology 1970, 7(1):1-8.
  • [36]Finderle Z, Cankar K: Delayed treatment of frostbite injury with hyperbaric oxygen therapy: a case report. Aviat Space Environ Med 2002, 73(4):392-394.
  • [37]Taylor MS: Lumbar epidural sympathectomy for frostbite injuries of the feet. Military Med 1999, 164(8):566-567.
  • [38]Ervasti O, Hassi J, Rintamaki H, Virokannas H, Kettunen P, Pramila S, Linna T, Tolonen U, Manelius J: Sequelae of moderate finger frostbite as assessed by subjective sensations, clinical signs, and thermophysiological responses. Int J Circumpol Heal 2000, 59(2):137-145.
  • [39]Carrera GF, Kozin F, Flaherty L, McCarty DJ: Radiographic changes in the hands following childhood frostbite injury. Skeletal Radiol 1981, 6(1):33-37.
  • [40]Bigelow DR, Boniface S, Ritchie GW: The effects of frostbite in childhood. J Bone Joint Surg 1963, 45B(1):122-131.
  • [41]Rossis CG, Yiacoumettis AM, Elemenoglou J: Squamous cell carcinoma of the heel developing at site of previous frostbite. J R Soc Med 1982, 75(9):715-718.
  • [42]Russell KW, Imray CH, McIntosh SE, Anderson R, Galbraith D, Hudson ST, Cochran AL: Kite skier's toe: an unusual case of frostbite. Wilderness Environ Med 2013, 24(2):136-140. doi:10.1016/j.wem.2012.11.013
  • [43]British Mountaineering Council: How to get expert frostbite advice. [https://www.thebmc.co.uk/how-to-get-expert-frostbite-advice webcite]
  文献评价指标  
  下载次数:63次 浏览次数:21次