A 57-year-old Brazilian woman with a giant mucinous cystadenocarcinoma of the ovary: a case report

Journal of Medical Case Reports

Fabiana Ruas Domingues Modesto²  Victor Paranaíba Campos¹  Andersen Charles Darós⁴  Vitorino Modesto dos Santos⁵  Sergio Henrique Mattioda de Lima³ 

[1]Gynecology and Obstetrics Division of Brasilia University Hospital (HUB), Brasília-DF, Brazil

[2]Brazilian Federation of Gynecology and Obstetrics (Febrasgo), São Paulo-SP, Brazil

[3]Gynecology and Obstetrics Division of Armed Forces Hospital (HFA) and South Wing Regional Hospital (HRAS), Brasília-DF, Brazil

[4]Pathology Division of HFA, and HRAS, Brasília-DF, Brazil

[5]Department of Medicine, Armed Forces Hospital (HFA), Estrada do Contorno do Bosque s/n, Cruzeiro Novo, 70630-900 Brasília-DF, Brazil

关键词: Tumor;    Ovary;    Mucinous;    Cystadenocarcinoma;    Giant;   

Others  :  822605
DOI  :  10.1186/1752-1947-8-82

 received in 2013-09-20, accepted in 2014-01-06,  发布年份 2014

【 摘 要 】

Introduction

Giant cystadenocarcinomas of the ovary are rarely described conditions.

Case presentation

The authors describe a 57-year-old Brazilian woman who presented with an increase in abdominal girth in February 2003. Imaging studies showed a giant abdominal pelvic mass with probable origin in the right ovary. Cancer antigen-125 was elevated, while carcinoembrionic antigen and alpha-fetoprotein were normal. Total abdominal hysterectomy, bilateral salpingoophorectomy and omentectomy were done. The mass weighed 40Kg, and the histopathology study revealed a mucinous cystadenocarcinoma. She underwent chemotherapy with paclitaxel and cisplatin with no side effects. Under follow-up for more than 10 years, she is asymptomatic and with normal imaging and laboratory parameters, including the cancer antigen-125 marker.

Conclusion

This huge tumor evolved for a long time unsuspected and without metastases in a patient from a developing region. The diagnostic and management challenges posed by this unexpected and unusual presentation of an ovarian cystadenocarcinoma are discussed.

【 授权许可】

   
2014 de Lima et al.; licensee BioMed Central Ltd.

【 图 表 】

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【 参考文献 】

• [1]Gorgone S, Minniti C, Ilaqua A, Barbuscia M: Giant mucinous cystadenoma in a young patient. A case report. G Chir 2008, 29:42-44.
• [2]Cevik M, Guldur ME: An extra-large ovarian mucinous cystadenoma in a premenarchal girl and a review of the literature. J Pediatr Adolesc Gynecol 2013, 26:22-26.
• [3]Jones DR, Vasilakis A, Pillai L, Timberlake GA: Giant, benign, mucinous cystadenoma of the ovary: case study and literature review. Am Surg 1992, 58:400-403.
• [4]Kuşcu NK, Cağlar H, Ishakoğlu M, Kandiloğlu AR, Keleş GT: Giant mucinous cystadenocarcinoma: a case report. Arch Gynecol Obstet 2003, 267:158-159.
• [5]Nakamura M, Saitoh M, Miyamoto S, Kubo Y, Tomita H, Andoh A: Case of a giant mucinous ovarian carcinoma with bone metastasis. J Obstet Gynaecol Res 2005, 31:576-578.
• [6]O’Hanlan KA: Resection of a 303.2-pound ovarian tumor. Gynecol Oncol 1994, 54:365-371.
• [7]Poole SY, Malone JM Jr, Jacques SM, James A: Giant mucinous ovarian tumor with low malignant potential with foci of well-differentiated mucinous adenocarcinoma masked by massive obesity. A case report. J Reprod Med 1994, 39:982-984.
• [8]Dolan MS, Boulanger SC, Salameh JR: Laparoscopic management of giant ovarian cyst. JSLS 2006, 10:254-256.
• [9]Göçmen A, Atak T, Uçar M, Sanlikal F: Laparoscopy-assisted cystectomy for large adnexal cysts. Arch Gynecol Obstet 2009, 279:17-22.
• [10]Santos VM, Barbosa ER Jr, Lima SH, Porto AS: Abdominal cocoon associated with endometriosis. Singapore Med J 2007, 48:e240-e242.
• [11]Dos Santos VM, de Almeida AC A, de Carvalho Santos S, Machado Lima RL, Fastudo CA: Unsuspected giant hydatid cyst of the liver in an 87-year-old woman. Infez Med 2011, 19:185-188.
• [12]Willems RP, Slangen B, Busari JO: Abdominal swelling in two teenage girls: two case reports of massive ovarian tumours in puberty. BMJ Case Rep 2012. doi: 10.1136/bcr.11.2011.5143
• [13]Zanini P, Cavalca A, Benatti E, Drei B: Benign giant ovarian cystadenoma. Description of a clinical case. Minerva Ginecol 1996, 48:215-219.
• [14]Chakrabarti S, Konar A, Biswas S, Das S: Sarcoma-like mural nodules in ovarian mucinous cystadenomas - a report of two cases. Indian J Med Sci 2005, 59:499-502.
• [15]Heinen FL, Pérez G: Ovarian mucinous borderline cystadenoma, in a premenarchal girl. Arch Argent Pediatr 2012, 110:e4-8.
• [16]Tokuda Y, Chinen K, Obara H, Joishy SK: Intervals between symptom onset and clinical presentation in cancer patients. Intern Med 2009, 48:899-905.