期刊论文详细信息
Journal of Medical Case Reports
Nonabsorbable suture granuloma mimicking ovarian cancer recurrence at combined positron emission tomography/computed tomography evaluation: a case report
Pierluigi Benedetti Panici1  Innocenza Palaia1  Primo Pennesi1  Elisa Bevilacqua1  Angela Musella1  Lucia di Francesco1  Laura Vertechy1  Carlotta Bracchi1  Roberta Iadarola1  Laura Salerno1  Claudia Marchetti1  Ludovica Imperiale1 
[1] Department of Gynecological and Obstetrical Sciences and Urological Sciences, Sapienza University of Rome, Via del Policlinico, 155, 00161 Rome, Italy
关键词: Surgery;    Foreign body;    Diagnosis;    Cancer;   
Others  :  817505
DOI  :  10.1186/1752-1947-8-202
 received in 2014-01-30, accepted in 2014-04-22,  发布年份 2014
PDF
【 摘 要 】

Introduction

This is the first case of suture granuloma mimicking isolated ovarian cancer relapse. Only six analogous cases have been previously reported in other malignancies.

Case presentation

We report the case of a 44-year-old Caucasian woman with partially platinum-sensitive ovarian cancer in which radiological features, including computed tomography and combined 18F-fluorodeoxyglucose-positron emission tomography/computed tomography, were strongly suggestive of isolated cancer relapse in her right subdiaphragmatic region. Laparoscopic examination resulted negative, but was not completely suitable due to widespread adhesive syndrome. The laparotomy for secondary cytoreductive surgery and biopsy of the suspected area showed inflammatory granuloma caused by nonabsorbable propylene suture, without evidence of neoplastic cells. Moreover, unexpected peritoneal carcinosis was found.

Conclusions

This evidence suggests that clinical details about previous surgical procedures are necessary for adequate interpretation. Although much progress has been made in imaging techniques, especially in the promising field of combined 18F-fluorodeoxyglucose positron emission tomography/computed tomography, these procedures should be still thoroughly investigated in order to promptly rule out tumor recurrence and avoid unnecessary surgery.

【 授权许可】

   
2014 Imperiale et al.; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20140711004932175.pdf 1516KB PDF download
Figure 3. 55KB Image download
Figure 2. 71KB Image download
Figure 1. 111KB Image download
【 图 表 】

Figure 1.

Figure 2.

Figure 3.

【 参考文献 】
  • [1]Güth U, Huang DJ, Bauer G, Stieger M, Wight E, Singer G: Metastatic patterns at autopsy in patients with ovarian carcinoma. Cancer 2007, 110:1272-1280.
  • [2]Park CM, Kim SH, Kim SH, Moon MH, Kim KW, Choi HJ: Recurrent ovarian malignancy: patterns and spectrum of imaging findings. Abdom Imaging 2003, 28:404-415.
  • [3]Chi DS, McCaughty K, Diaz JP, Huh J, Schwabenbauer S, Hummer AJ, Venkatraman ES, Aghajanian C, Sonoda Y, Abu-Rustum NR, Barakat RR: Guidelines and selection criteria for secondary cytoreductive surgery in patients with recurrent, platinum-sensitive epithelial ovarian carcinoma. Cancer 2006, 106:1933-1939.
  • [4]Pisano C, Bruni GS, Facchini G, Marchetti C, Pignata S: Treatment of recurrent epithelial ovarian cancer. Ther Clin Risk Manag 2009, 5:421-426.
  • [5]Lim JW, Tang CL, Keng GH: False positive F-18 fluorodeoxyglucose combined PET/CT scans from suture granuloma and chronic inflammation: report of two cases and review of literature. Ann Acad Med Singapore 2005, 34:457-460.
  • [6]Yüksel M, Akgül AG, Evman S, Batirel HF: Suture and stapler granulomas: a word of caution. Eur J Cardiothorac Surg 2007, 31:563-565.
  • [7]Kikuchi M, Nakamoto Y, Shinohara S, Fujiwara K, Tona Y, Yamazaki H, Kanazawa Y, Kurihara R, Imai Y, Naito Y: Suture granuloma showing false-positive finding on PET/CT after head and neck cancer surgery. Auris Nasus Larynx 2012, 39:94-97.
  • [8]Benedetti Panici P, De Vivo A, Bellati F, Manci N, Perniola G, Basile S, Muzii L, Angioli R: Secondary cytoreductive surgery in patients with platinum-sensitive recurrent ovarian cancer. Ann Surg Oncol 2007, 14:1136-1142.
  • [9]De Iaco P, Musto A, Orazi L, Zamagni C, Rosati M, Allegri V, Cacciari N, Al-Nahhas A, Rubello D, Venturoli S, Fanti S: FDG-PET/CT in advanced ovarian cancer staging: value and pitfalls in detecting lesions in different abdominal and pelvic quadrants compared with laparoscopy. Eur J Radiol 2011, 80:98-103.
  • [10]Aletti GD, Dowdy SC, Podratz KC, Cliby WA: Surgical treatment of diaphragm disease correlates with improved survival in optimally debulked advanced stage ovarian cancer. Gynecol Oncol 2006, 100:283-287.
  • [11]Chi DS, Zivanovic O, Levinson KL, Kolev V, Huh J, Dottino J, Gardner GJ, Leitao MM Jr, Levine DA, Sonoda Y, Abu-Rustum NR, Brown CL, Barakat RR: The incidence of major complications after the performance of extensive upper abdominal surgical procedures during primary cytoreduction of advanced ovarian, tubal, and peritoneal carcinomas. Gynecol Oncol 2010, 119:38-42.
  • [12]Kim HS, Chung TS, Suh SH, Kim SY: MR imaging findings of paravertebral gossypiboma. AJNR Am J Neuroradiol 2007, 28:709-713.
  • [13]Prakash P, Cronin CG, Blake MA: Role of PET/CT in ovarian cancer. AJR Am J Roentgenol 2010, 194:464-470.
  • [14]Son H, Khan SM, Rahaman J, Cameron KL, Prasad-Hayes M, Chuang L, Machac J, Heiba S, Kostakoglu L: Role of FDG PET/CT in staging of recurrent ovarian cancer. Radiographics 2011, 31:569-583.
  • [15]Chung HH, Kang WJ, Kim JW, Park NH, Song YS, Chung JK, Kang SB, Lee HP: Role of [18F] FDG PET/CT in the assessment of suspected recurrent ovarian cancer: correlation with clinical or histological findings. Eur J Nucl Med Mol Imaging 2007, 34:480-486.
  文献评价指标  
  下载次数:0次 浏览次数:3次