期刊论文详细信息
Clinical and Molecular Allergy
Effects of dexamethasone on TNF-alpha-induced release of cytokines from purified human blood eosinophils
Francesca Levi-Schaffer1  Keith P Ray2  Dilniya Fattah2  Susan J Smith1  Vladislav Temkin1  Ilaria Puxeddu1  Iain Uings2 
[1] Department of Pharmacology, School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem, Israel;Cell Biology Unit, Glaxo Wellcome SKB, Gunnels Wood Stevenage, Herts, SG1 2NY, UK
关键词: cytokine;    allergic inflammation;    dexamethasone;    eosinophils;    TNF-α;   
Others  :  792758
DOI  :  10.1186/1476-7961-3-5
 received in 2005-01-11, accepted in 2005-04-27,  发布年份 2005
PDF
【 授权许可】

   
2005 Uings et al; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20140705035556334.pdf 224KB PDF download
【 参考文献 】
  • [1]Levi-Schaffer F, Temkin V, Malamud V, Feld S, Zilberman Y: Mast cells enhance eosinophil survival in vitro: role of TNF-α and granulocyte-macrophage colony-stimulating factor. J Immunol 1998, 160:5554-5562.
  • [2]Lamas AM, Leon OG, Scleimer RP: Glucocorticosteroids inhibit eosinophil responses to granulocyte-macrophage colony-stimulating factor. J Immunol 1991, 147:254-259.
  • [3]Lim LH, Flower RJ, Pereti M, Das AM: Glucocorticoid receptor activation reduces CD11b and CD49d levels on murine eosinophils: characterization and functional relevance. Am J Respir Cell Mol Biol 2000, 22:693-701.
  • [4]Miyamasu M, Misaki Y, Izumi S, Takaishi T, Morita Y, Nakamura Y, et al.: Glucocorticoids inhibit chemokines generation by human eosinophils. J Allergy Clin Immunol 1998, 101:75-83.
  • [5]Fattah D, Page KR, Bezbararuah S, Priest RC, Horgan CM, Solari R: A rapid activation assay for human eosinophils based on adhesion to immobilised ICAM-1, VCAM-1 and IgG. Cytokine 1996, 8:248-259.
  • [6]Woolley MJ, Denburg JA, Ellis R, Dahlback M, O'Byrne PM: Allergen-induced changes in bone marrow progenitors and airway responsiveness in dogs and the effect of inhaled budesonide on these parameters. Am J Respir Cell Mol Biol 1994, 11:600-606.
  • [7]Inman MD, Denburg JA, Ellis R, Dahlback M, O'Byrne PM: The effect of treatment with budesonide or PGE2 in vitro on allergen-induced increases in canine bone marrow progenitors. Am J Respir Cell Mol Biol 1997, 17:634-641.
  • [8]Meagher LC, Cousin JM, Seckl JR, Haslett C: Opposing effects of glucocorticosteroids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes. J Immunol 1996, 156:4422-4428.
  • [9]Adcock IM: Glucocorticosteroid-regulated transcription factors. Pulm Pharmacol Ther 2001, 14:211-219.
  • [10]Fujihara S, Ward C, Dransfield I, Hay RT, Uings IJ, Hayes B, Farrow SN, Haslett C, Rossi AG: Inhibition of nuclear factor-kappaB activation un-masks the ability of TNF-alpha to induce human eosinophil apoptosis. Eur J Immunol 2002, 32:457-466.
  • [11]Kita H, Abu-Ghazaleh R, Sanderson CJ, Gleich GJ: Effect of steroids on immunoglobulin-induced eosiniophil degranulation. J Allergy Clin Immunol 1991, 87:70-77.
  • [12]Falkenstein E, Tillmann HC, Christ M, Feuring M, Wehling M: Multiple actions of steroid hormones: a focus on rapid, non-genomic effects. Pharmacol Rev 2000, 52:513-556.
  文献评价指标  
  下载次数:9次 浏览次数:16次