Identification of tetrodotoxin-producing Shewanella spp. from feces of food poisoning patients and food samples

Gut Pathogens

Biao Kan³  Di Xiao³  Jie Lin¹  Hongnan Huang¹  Yonglu Wang²  Duochun Wang³ 

[1] Center for Diseases Control and Prevention of Fujian Province, Fujian, China;Ma’anshan Center for Disease Control and Prevention, Ma’anshan, China;State Key Laboratory for Infectious Disease Prevention and Control/Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, P.O. Box 5, Beijing, Changping, China

关键词: Food poisoning;    Shewanella;    Tetrodotoxin;   

Others  :  821444
DOI  :  10.1186/1757-4749-5-15

 received in 2013-04-09, accepted in 2013-06-15,  发布年份 2013

【 摘 要 】

Shewanella spp. is infrequently recovered from clinical specimens. Following two outbreaks of food poisoning, eight Shewanella spp. strains were obtained from the fecal specimens of patients, food and food processing-related materials. Tetrodotoxin (TTX) was identified in the culture supernatants of these strains, and the toxin’s biological activity was detected using a mouse bioassay. This study suggested that Shewanella strains can colonize and survive in human intestines. The study also raises the issues of the accumulation of TTX produced by Shewanella in food and the possible role of TTX-producing Shewanella in food poisoning.

【 授权许可】

   
2013 Wang et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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