Developmental programming: the role of growth hormone

Journal of Animal Science and Biotechnology

Anita M Oberbauer¹ 

[1] Department of Animal Science, University of California, One Shields Ave, Davis 95616, CA, USA

关键词: Transgeneration;    Programming;    Growth hormone;    Epigenetic;   

Others  :  1139204
DOI  :  10.1186/s40104-015-0001-8

 received in 2014-09-18, accepted in 2015-01-20,  发布年份 2015

【 摘 要 】

Developmental programming of the fetus has consequences for physiologic responses in the offspring as an adult and, more recently, is implicated in the expression of altered phenotypes of future generations. Some phenotypes, such as fertility, bone strength, and adiposity are highly relevant to food animal production and in utero factors that impinge on those traits are vital to understand. A key systemic regulatory hormone is growth hormone (GH), which has a developmental role in virtually all tissues and organs. This review catalogs the impact of GH on tissue programming and how perturbations early in development influence GH function.

【 授权许可】

   
2015 Oberbauer; licensee BioMed Central.

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