Transient Polycomb activity represses developmental genes in growing oocytes

Clinical Epigenetics

Research

Qing-hua Zhang¹  Jessica M. Stringer¹  John Carroll¹  Natalie A. Sims²  Ruby Oberin³  Sigrid Petautschnig³  Tesha Tsai³  Patrick S. Western³  Heidi Bildsoe³  Ellen G. Jarred³  William T. Gibson⁴  Zhipeng Qu⁵  Stephen Pederson⁵  David L. Adelson⁶  David K. Gardner⁷  Maarten Van den Buuse⁸ 

[1] Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia;Bone Cell Biology and Disease Unit, St. Vincent’s Institute of Medical Research, Fitzroy, VIC, Australia;Department of Medicine at St, Vincent’s Hospital, Fitzroy, VIC, Australia;Centre for Reproductive Health, Hudson Institute of Medical Research, Clayton, VIC, Australia;Department of Molecular and Translational Science, Monash University, Clayton, VIC, Australia;Department of Medical Genetics, University of British Columbia and British Columbia Children’s Hospital Research Institute, Vancouver, BC, Canada;Department of Molecular and Biomedical Science, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia;Department of Molecular and Biomedical Science, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia;South Australian Museum, Adelaide, SA, Australia;School of BioSciences, University of Melbourne, Parkville, VIC, Australia;School of Psychology and Public Health, La Trobe University, Melbourne, VIC, Australia;

关键词: Polycomb;    Oocyte;    Programming;    Epigenetic;    H3K27me3;    Inheritance;   

DOI  :  10.1186/s13148-022-01400-w

 received in 2022-06-21, accepted in 2022-12-06,  发布年份 2022

来源: Springer

【 授权许可】

CC BY   
© The Author(s) 2022

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