Comparison of high and low intensity contact between secondary and primary care to detect people at ultra-high risk for psychosis: study protocol for a theory-based, cluster randomized controlled trial

Trials

Peter B Jones⁶  Tim J Croudace²  Michelle Painter³  Jonathan P Graffy⁵  Jorge Zimbron¹  Sarah Byford⁴  Jan Stochl¹  Debra A Russo¹  Jesus Perez¹ 

[1] Department of Psychiatry, Herchel Smith Building for Brain and Mind Sciences, University of Cambridge, Forvie Site, Robinson Way, Cambridge, UK;Department of Health Sciences, Seebohm Rowntree Building, University of York, Heslington, York, YO10 5DD, UK;CAMEO Early Intervention Services, Cambridgeshire and Peterborough NHS Foundation Trust, Ida Darwin, Fulbourn, Block 7, Ida Darwin, Fulbourn, Cambridge, CB21 5EE, UK;Centre for the Economics of Mental and Physical Health, Institute of Psychiatry, King's College London, 16 De Crespigny Park, London, SE5 8AF, UK;Primary Care Unit, Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Forvie Site, Robinson Way, Cambridge, CB2 0SR, UK;National Institute of Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care for Cambridgeshire and Peterborough (CLAHRC-CP), 18 Trumpington Road, Cambridge, CB2 8AH, UK

关键词: Ultra high-risk;    Cluster randomized controlled trial;    Psychosis;    Primary care;    Early intervention;   

Others  :  1093392
DOI  :  10.1186/1745-6215-14-222

 received in 2012-10-10, accepted in 2013-07-03,  发布年份 2013

【 摘 要 】

Background

The early detection and referral to specialized services of young people at ultra-high risk (UHR) for psychosis may reduce the duration of untreated psychosis and, therefore, improve prognosis. General practitioners (GPs) are usually the healthcare professionals contacted first on the help-seeking pathway of these individuals.

Methods/Design

This is a cluster randomized controlled trial (cRCT) of primary care practices in Cambridgeshire and Peterborough, UK. Practices are randomly allocated into two groups in order to establish which is the most effective and cost-effective way to identify people at UHR for psychosis. One group will receive postal information about the local early intervention in psychosis service, including how to identify young people who may be in the early stages of a psychotic illness. The second group will receive the same information plus an additional, ongoing theory-based educational intervention with dedicated liaison practitioners to train clinical staff at each site. The primary outcome of this trial is count data over a 2-year period: the yield - number of UHR for psychosis referrals to a specialist early intervention in psychosis service - per primary care practice.

Discussion

There is little guidance on the essential components of effective and cost-effective educational interventions in primary mental health care. Furthermore, no study has demonstrated an effect of a theory-based intervention to help GPs identify young people at UHR for psychosis. This study protocol is underpinned by a robust scientific rationale that intends to address these limitations.

Trial registration

Current Controlled Trials ISRCTN70185866

【 授权许可】

   
2013 Perez et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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