Phytochemical composition and antimicrobial activities of the essential oils and organic extracts from pelargonium graveolens growing in Tunisia

Lipids in Health and Disease

Naceur Hamdi²  Anis Ben Hsouna¹ 

[1] Bio-pesticides Team (LPIP), Center of Biotechnology of Sfax, P.B. 1177, Sfax, 3018, Tunisia;Higher Institute of Environmental Science and Technology, Borj-Cédria, TUNISIA" & "University of Carthage, Carthage, Tunisia

关键词: GC/MS;    Organic extracts;    Essential oils;    Antimicrobial activity;    P. graveolens;   

Others  :  1160123
DOI  :  10.1186/1476-511X-11-167

 received in 2012-10-04, accepted in 2012-11-28,  发布年份 2012

【 摘 要 】

Background

Pelargonium graveolens (P. graveolens) L. is an aromatic and medicinal plant belonging to the geraniacea family.

Results

The chemical compositions of the essential oil as well as the in vitro antimicrobial activities were investigated. The GC-MS analysis of the essential oil revealed 42 compounds. Linallol L, Citronellol, Geraniol, 6-Octen-1-ol, 3,7-dimethyl, formate and Selinene were identified as the major components. The tested oil and organic extracts exhibited a promising antimicrobial effect against a panel of microorganisms with diameter inhibition zones ranging from 12 to 34 mm and MIC_s values from 0.039 to10 mg/ml. The investigation of the phenolic content showed that EtOAc, MeOH and water extracts had the highest phenolic contents.

Conclusion

Overall, results presented here suggest that the essential oil and organic extracts of P. graveolens possesses antimicrobial and properties, and is therefore a potential source of active ingredients for food and pharmaceutical industry.

【 授权许可】

   
2012 Ben Hsouna and Hamdi; licensee BioMed Central Ltd.

【 参考文献 】

• [1]Tepe B, Daferera D, Sokmen A, Sokmen M, Polissiou M: Antimicrobial and antioxidant activities of essential oil and various extracts of salvia tomentosa miller (lamiaceae). Food Chem 2005, 90:333-340.
• [2]Khanna D, Sethi G, Ahn KS, Pandey MK, Kunnumakkara AB, Sung B, Aggarwal A, Aggarwal BB: Natural products as a gold mine for arthritis treatment. Curr Opin Pharmacol 2007, 7:344-351.
• [3]Fusco D, Colloca G, Lo Monaco MR, Cesari M: Rationale for antioxidant supplementation in sarcopenia. J Clin Interv Aging 2007, 2:377-387.
• [4]Loizzo MR, Tundis R, Conforti F, Saab AM, Statti GA, Menichini F: Composition and α-amylase inhibitory effect of essential oils from cedrus libani. Fitoterapia 2007, 78:323-326.
• [5]Saraswathi J, Venkatesh K, Baburao N, Hilal MH, Roja Rani A: Phytopharmacological importance of pelargonium species. Journal of Medicinal Plants Research 2011, 5:2587-2598.
• [6]Mativandlela SPN, Lall N, Meyer JJN: Antibacterial, antifungal and antitubercular activity of (the roots of) Pelargonium reniforme (CURT) and Pelargonium sidoides (DC) (Geraniaceae) root extracts. South African Journal of Botany 2006, 72:232-237.
• [7]Ben Hsouna A, Trigui M, Ben Mansour R, Mezghani Jarraya R, Damak M, Jaoua S: Chemical composition, cytotoxicity effect and antimicrobial activity of ceratonia siliqua essential oil with preservative effects against Listeria inoculated in minced beef meat. Int J Food Microbiol 2011, 148:66-72.
• [8]Sartoratto A, Machado ALM, Delarmelina C, Figueira GM, Duarte MCT, Rehder VLG: Composition and antimicrobial activity of essential oils from aromatic plants used in brazil. Braz J Microbiol 2004, 35:275-280.
• [9]Ben Hsouna A, Culioli MG, Blache Y, Jaoua S: Antioxidant constituents from lawsonia inermis leaves: isolation, structure elucidation and antioxidative capacity. Food Chem 2011, 125:193-200.
• [10]Quettier-Deleu C, Gressier B, Vasseur J, Dine T, Brunet C, Luyck M, Cazin M, Cazin JC, Bailleul F, Trotin F: Phenolic compounds and antioxidant activities of buckwheat (fagopyrum esculentum moench) hulls and flour. J Ethnopharmacol 2000, 72:35-42.
• [11]Fendri I, Chaari A, Dhouib A, Jlassi B, Carriere F, Sayadi S, Abdelkafi S: Isolation, identification and characterization of a new lipolytic pseudomonas sp., strain AHD-1, from Tunisian soil. Environ Technol 2010, 31:87-95.
• [12]Barouh N, Abdelkafi S, Fouquet B, Pina M, Scheirlinckx F, Carrière F, Villeneuve P: Neutral lipid characterization of non-water-soluble fractions of carica papaya latex. Journal of American Oil Chemist Society 2010, 87:987-995.
• [13]Güven K, Yücel E, Çetintaş F: Antimicrobial activities of fruits of crataegus and pyrus species. Pharm Biol 2006, 44:79-83.
• [14]Gulluce M, Sahin F, Sokmen M, Ozer H, Daferera D, Sokmen A, Polissiou M, Adiguzel A, Ozkan H: Antimicrobial and antioxidant properties of the essential oils and methanol extract from mentha longifolia L. ssp. Longifolia. Food Chem 2007, 103:1449-1456.
• [15]Shojaee-Aliabadi S, Hosseini H, Mohammadifar MA, Mohammadi A, Ghasemlou M, Mahdi Ojagh S, Marzieh Hosseini S, Khaksar R: Characterization of antioxidant-antimicrobial κ-Carrageenan films containing satureja hortensis essential oil. Int J Biol Macromol 2012. In Press
• [16]Gupta S, Prakash J: Studies on indian green leafy vegetables for their antioxidant activity. Plant Foods Hum Nutr 2009, 64:39-45.
• [17]Boukhris M, Simmonds MSJ, Sayadi S, Bouaziz M: Chemical composition and biological activities of polar extracts and essential oil of rose-scented geranium, Pelargonium graveolens. Phytother Res 2012.
• [18]Hertog MGL, Hollman PCH, Van de Putte B: Content of potentially anticarcinogenic flavonoids of tea infusions, wines, and fruit juices. Journal Agricultrual Food Chemistry 1993, 41:1242-1246.
• [19]Yen G, Wu S, Duh P: Extraction and identification of antioxidant components from the leaves of mulberry (morus alba L.). Journal Agricultrual Food Chemistry 1996, 44:1687-1690.
• [20]Ardestani A, Yazdanparast R: Antioxidant and free radical scavenging potential of achillea santolina extracts. Food Chem 2007, 104:21-29.
• [21]Djeridane A, Yousfi M, Nadjemi B, Boutassouna D, Stocker P, Vidal N: Antioxidant activity of some Algerian medicinal plants extracts containing Phenolic compounds. Food Chem 2006, 97:654-660.
• [22]Hussain AI, Anwar F, Shahid M, Ashraf M, Przybylski R: Chemical composition, antioxidant and antimicrobial activities of essential oil of spearmint (mentha spicata L.) from Pakistan. Journal Essential Oil Research 2010, 22:78-84.
• [23]Kordali S, Cakir A, Mavi A, Kilic H, Yildirim A: Screening of chemical composition and antifungal and antioxidant activities of the essential oils from three Turkish Artemisia species. J Agric Food Chem 2005, 53:1408-1416.