Visceral adiposity index score indicated the severity of coronary heart disease in Chinese adults

Diabetology & Metabolic Syndrome

Ming Zhong²  Wei Zhang²  Yun Zhang²  Hui Wang²  Jia Wang²  Meng-xiong Tang³  Zhi-hao Wang¹  Jing Zhao²  Kai-li Fu²  Lu Han² 

[1] Department of Geriatrics Medicine, Qilu Hospital of Shandong University, Ji’nan 250012, P.R. China;Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Public Health, Department of Cardiology, Qilu Hospital of Shandong University, No.107, Wen Hua Xi Road, Ji’nan 250012, P.R. China;Department of Emergency Medicine, Qilu Hospital of Shandong University, Ji’nan 250012, P.R. China

关键词: Diabetes;    Coronary heart disease;    Visceral adiposity index;   

Others  :  1128710
DOI  :  10.1186/1758-5996-6-143

 received in 2014-08-17, accepted in 2014-12-10,  发布年份 2014

【 摘 要 】

Background

Visceral adiposity contributes to cardiometabolic risk, and visceral adiposity index (VAI) had significant correlation with visceral adiposity. We aimed to explore whether VAI was associated with cardiac structure and function and assess the impact of the cut-off points of VAI defining visceral adipose dysfunction (VAD) on the severity of coronary heart disease (CHD).

Methods

A total of 95 patients with CHD were divided into Control (nondiabetic CHD patients) and DM group (diabetic CHD patients). Then the two groups were respectively divided into VAD absent and VAD groups. Clinical, echocardiographic and coronary artery angiographic indexes were acquired to examine in relation to VAI.

Results

A significant increasing trend among the four groups of patients (Control + VAD absent, Control +VAD, DM + VAD absent and DM +VAD groups) were observed for waist circumference (WC), body mass index (BMI), systolic blood pressure (SBP), glucose, VAI and Gensini score (P<0.05 for all). The following variables were associated with VAI: total cholesterol, nonesterified fatty acid, Waist-Hip ratio and SBP. VAI was independently associated with Gensini score.

Conclusions

The extent of CHD was more severe in diabetes, and VAI as a simple indicator of visceral adipose mass was strongly associated with the severity of CHD. The cut-off points of VAI used for defining VAD were more useful in diabetic CHD patients in identifying the severity of CHD.

【 授权许可】

   
2015 Han et al.; licensee BioMed Central.

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