BMC Veterinary Research | |
The use of micro-computed tomography in the diagnosis of dental and oral disease in rabbits | |
Yuki Izumi1  Eiko Seto1  Daisuke Fujita1  Hiroyuki Iwai1  Hiroshi Sasai1  | |
[1] Kitasuma Animal Hospital, Hyougo, 9-5-8 Yokoo Suma-ward, Kobe City 654-0131, Hyogo, Japan | |
关键词: Rabbit; Dentistry; Micro-CT; Computed tomography; | |
Others : 1119022 DOI : 10.1186/s12917-014-0209-4 |
|
received in 2013-09-18, accepted in 2014-08-28, 发布年份 2014 | |
【 摘 要 】
Background
The aim of this study was to investigate the use of a newly developed micro-computed tomography (micro-CT) system for the diagnosis of oral pathologies in small animals, using the rabbit as a model. The diagnosis of dental diseases in rabbits is usually based on oral endoscopy and radiographic imaging, but detailed pathological diagnosis using these methods is frequently difficult. Micro-CT was used in this study to address this challenge.
Results
This study was conducted using 50 privately owned rabbits, presented to our hospital due to loss of appetite or difficulty feeding. Image recording times were 18 s in normal mode and 120 s in fine mode. The animals were maintained in the required position for scanning via the administration of sedatives. Micro-CT captured with a slice thickness of 60–120 mm has excellent spatial resolution, and is suitable for the clinical diagnosis of dental diseases in rabbits weighing 1–3 kg.
Conclusions
Micro-CT can yield more detailed data than radiography or conventional CT. This study determined that this novel imaging modality can be utilized for the accurate assessment of dental and oral diseases in rabbits.
【 授权许可】
2014 Sasai et al.; licensee BioMed Central Ltd.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
20150208040211220.pdf | 1394KB | download | |
Figure 7. | 115KB | Image | download |
Figure 6. | 32KB | Image | download |
Figure 5. | 21KB | Image | download |
Figure 4. | 53KB | Image | download |
Figure 3. | 177KB | Image | download |
Figure 2. | 167KB | Image | download |
Figure 1. | 30KB | Image | download |
【 图 表 】
Figure 1.
Figure 2.
Figure 3.
Figure 4.
Figure 5.
Figure 6.
Figure 7.
【 参考文献 】
- [1]Capello V, Lennox AM: Small mammal dentistry. In Ferrets, Rabbits, and Rodents. 3rd edition. W.B. Saunders, Saint Louis; 2012:452-471.
- [2]Verstraete FJM, Osofsky A: Dentistry in pet rabbits. Compend Contin Educ Vet 2005, 27(9):671-684.
- [3]Capello V, Cauduro A: Clinical technique: application of computed tomography for diagnosis of dental disease in the rabbit, guinea pig, and chinchilla. Journal of Exotic Pet Medicine 2008, 17(2):93-101.
- [4]Ritman EL: Current status of developments and applications of micro-CT. Annu Rev Biomed Eng 2011, 13:531-552.
- [5]Roza MR, Silva LAF, Barriviera M, Januário AL, Bezerra ACB, Fioravanti MCS: Cone beam computed tomography and intraoral radiography for diagnosis of dental abnormalities in dogs and cats. J Vet Sci 2011, 12(4):387-392.
- [6]Badea CT, Drangova M, Holdsworth DW, Johnson GA: In vivo small-animal imaging using micro-CT and digital subtraction angiography. Phys Med Biol 2008, 53(19):R319-350.
- [7]De Rycke LM, Boone MN, Van Caelenberg AI, Dierick M, Van Hoorebeke L, van Bree H, Gielen IM: Micro-computed tomography of the head and dentition in cadavers of clinically normal rabbits. Am J Vet Res 2012, 73(2):227-232.
- [8]Van Thielen B, Siguenza F, Hassan B: Cone beam computed tomography in veterinary dentistry. J Vet Dent 2012, 29(1):27-34.
- [9]Van Caelenberg AI, De Rycke LM, Hermans K, Verhaert L, Van Bree HJ, Gielen IM: Comparison of radiography and CT to identify changes in the skulls of four rabbits with dental disease. J Vet Dent 2011, 28(3):172-181.
- [10]Arai Y, Yamada A, Ninomiya T, Kato T, Masuda Y: Micro-computed tomography newly developed for in vivo small animal imaging. Oral Radiology 2005, 21(1):14-18.
- [11]Hasuike A, Sato S, Udagawa A, Ando K, Arai Y, Ito K: In vivo bone regenerative effect of low-intensity pulsed ultrasound in rat calvarial defects. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011, 111(1):e12-20.
- [12]Kameoka S, Kuroki Y, Honda K, Kijima N, Matsumoto K, Asano M, Arai Y, Shirakawa T: Diagnostic accuracy of microcomputed tomography for osseous abnormalities in the rat temporomandibular joint condyle. Dentomaxillofac Radiol 2009, 38(7):465-469.
- [13]Kameoka S, Matsumoto K, Kai Y, Yonehara Y, Arai Y, Honda K: Establishment of temporomandibular joint puncture technique in rats using in vivo micro-computed tomography (R_mCT®). Dentomaxillofac Radiol 2010, 39(7):441-445.
- [14]Min S, Sato S, Saito M, Ebihara H, Arai Y, Ito K: Micro-computerized tomography analysis: dynamics of bone augmentation within a titanium cap in rabbit calvarium. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008, 106(6):892-895.
- [15]Brodbelt DC, Blissitt KJ, Hammond RA, Neath PJ, Young LE, Pfeiffer DU, Wood JL: The risk of death: the confidential enquiry into perioperative small animal fatalities. Vet Anaesth Analg 2008, 35(5):365-373.