Evaluation of health related quality of life in irritable bowel syndrome patients

Health and Quality of Life Outcomes

Naser Ebrahimi Daryani⁵  Shahab Dolatshahi⁶  Reza Ansari⁶  Neda Moslemi¹  Bardia Jamali⁴  Abdollah Omidi²  Maryam Poorrahnama⁴  Arsia Jamali⁴  Raika Jamali³ 

[1] Laser Research Center of Dentistry, Dental Research Center, Tehran University of Medical Sciences, Tehran, Iran;Department of Clinical Psychiatry, Kashan University of Medical Sciences, Kashan, Iran;Anatomical Sciences Research Center, Students' Scientific Research Center, Kashan University of Medical Sciences, Kashan, Iran;Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran;Department of Gastroenterology, Tehran University of Medical Sciences, Tehran, Iran;Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran

关键词: Depression;    Anxiety;    Gender;    Irritable bowel syndrome;    Quality of life;   

Others  :  825982
DOI  :  10.1186/1477-7525-10-12

 received in 2011-11-11, accepted in 2012-01-29,  发布年份 2012

【 摘 要 】

Background

Quality of life (QOL) is an important measure in the management of Irritable Bowel Syndrome (IBS). Controversy exists in the findings of studies evaluating QOL in IBS subtypes, and little is known about this issue in Iranian patients. Determination of the factors affecting QOL in IBS patients may influence treatment outcomes. The aims of this study are to: 1) compare QOL between subtypes in a sample of Iranian IBS patients, 2) determine the factors associated with QOL in IBS.

Methods

This cross sectional study included two hundred and fifty IBS patients with the mean age (± standard deviation) of 31.62 (± 11.93) years that were referred to outpatient gastroenterology clinic. IBS patients were diagnosed based on Rome-3 criteria by a gastroenterologist, and then they were categorized into three subtypes according to the predominant type of bowel habit. The "QOL specific for IBS", "Stait-trait anxiety inventory", and "Beck depression inventory-2" questioners were used to evaluate QOL, anxiety, and depression symptoms, respectively.

Results

The mean QOL scores in IBS mixed subtype (71.7 ± 25.57), constipation predominant subtype (80.28 ± 25.57), and diarrhea predominant subtype (76.43 ± 19.13) were not different. (P value: 0.05) In multivariate linear regression analysis, anxiety symptom scores were inversely correlated with QOL scores. [Standardized beta: -0.43, (95% confidence interval: -0.70, -0.39), P value: < 0.01]

Conclusion

It seems reasonable to manage anxiety symptoms properly in IBS patients since this might increase their QOL.

【 授权许可】

   
2012 Jamali et al; licensee BioMed Central Ltd.

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