A new diagnostic vestibular evoked response

Journal of Otolaryngology-Head & Neck Surgery

Zahra Moussavi⁴  Brian Blakley¹  Brian Lithgow³  Zeinab A Dastgheib² 

[1] Department of Otolaryngology - Head and Neck Surgery, University of Manitoba, GB421 - 820 Sherbrook Street, Winnipeg R3A 1R9, Manitoba, Canada;Department of Electrical & Computer Engineering, University of Manitoba, Room E3-512 Eng. Bldg., 75A Chancellor’s Circle, Winnipeg R3T 5V6, MB, Canada;EVestG Research Lab, Riverview Health Centre, Room PE446, 1 Morley Avenue, Winnipeg R3L2P4, MB, Canada;Department of Electrical & Computer Engineering, University of Manitoba, 75A Chancellor’s Circle, Winnipeg R3T 5V6, MB, Canada

关键词: Fractal dimension;    Classification;    Vestibular response;    EVestG;    Meniere’s disease;   

Others  :  1172969
DOI  :  10.1186/s40463-015-0065-7

 received in 2014-06-24, accepted in 2015-01-20,  发布年份 2015

【 摘 要 】

Objective

To describe the development of a new clinically applicable method for assessing vestibular function in humans with particular application in Meniere’s disease.

Study design

Sophisticated signal-processing techniques were applied to data from human subject undergoing tilts stimulating the otolith organs and semicircular canals. The most sensitive representatives of vestibular function were extracted as “features”.

Methods

After careful consideration of expected response features, Electrovestibulography, a modified electrocochleography, recordings were performed on fourteen Meniere’s patients and sixteen healthy controls undergoing controlled tilts. The data were subjected to multiple signal processing techniques to determine which “features” were most predictive of vestibular responses.

Results

Linear discriminant analysis and fractal dimension may allow data from a single tilt to be used to adequately characterize the vestibular system.

Conclusion

Objective, physiologic assessment of vestibular function may become realistic with application of modern signal processing techniques.

【 授权许可】

   
2015 Dastgheib et al.; licensee BioMed Central.

【 图 表 】

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