Risk factors for Enterobius vermicularis infection in children in Gaozhou, Guangdong, China

Infectious Diseases of Poverty

Ying-Dan Chen¹  Long-Qi Xu¹  Ting-Jun Zhu¹  Qi-Ming Zhang²  Cai-Wen Ruan²  Zhuo-Hui Deng²  Zhi-Shi Li³  Chang-Hai Zhou¹  Hong-Mei Li¹ 

[1] National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborative Center for Malaria, Schistosomiasis and Filariasis, Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai 200025, China;Guangdong Center for Disease Control and Prevention, Guangzhou 510000, China;Gaozhou Center for Disease Control and Prevention, Gaozhou 515200, China

关键词: China;    Children;    Risk factor;    Prevalence;    Enterobius vermicularis;   

Others  :  1210516
DOI  :  10.1186/s40249-015-0058-9

 received in 2014-12-23, accepted in 2015-05-05,  发布年份 2015

【 摘 要 】

Background

Enterobius vermicularis infection is a prevalent intestinal parasitic disease in children. In this study, we explored the epidemiological status and risk factors for E. vermicularis infection in children in southern China.

Methods

A cross-sectional survey was carried out in Gaozhou city, Guangdong province, China, in December 2011. Children aged 2–12 years from five schools participated in the study. The adhesive cellophane-tape perianal swab method was applied to detect E. vermicularis infection, while a questionnaire was sent to each child’s guardian(s) to collect demographic and socioeconomic data, as well as hygiene behaviors, pertaining to each child. Univariate and multivariate logistic regression analyses were performed to capture the potential risk factors.

Results

Out of the 802 children surveyed, 440 were infected with E. vermicularis, with an average prevalence of 54.86 %, and a range from 45.96 to 68.13 %. The age variable was found to be statistically significant, whereas the sex variable was not. It was found that a mother’s education level (low) and not washing hands before dinner were major risk factors in all children (802). After stratification by age, a father’s education level (primary or below) and biting pencils (or toys) were significant risk factors in the younger children (508), while not washing hands before dinner and playing on the ground were important risk factors in the older children (294).

Conclusion

This study demonstrates the prevalence of E. vermicularis infection in children in Gaozhou and reveals underlying risk factors. Most importantly, it reveals that risk factors differ among the different age groups, which indicates that different control measures targeted at particular age groups should be implemented.

【 授权许可】

   
2015 Li et al. ; licensee BioMed Central.

【 图 表 】

Fig. 1.

【 参考文献 】

• [1]Chang TK, Liao CW, Huang YC, Chang CC, Chou CM, Tsay HC, et al.: Prevalence of Enterobius vermicularis Infection among preschool children in kindergartens of Taipei City, Taiwan in 2008. Korean J Parasitol 2009, 47:185-7.
• [2]Remm M, Remm K: Effectiveness of repeated examination to diagnose enterobiasis in nursery school groups. Korean J Parasitol 2009, 47:235-41.
• [3]Matthys B, Bobieva M, Karimova G, Mengliboeva Z, Jean-Richard V, Hoimnazarova M, et al.: Prevalence and risk factors of helminths and intestinal protozoa infections among children from primary schools in western Tajikistan. Parasit Vectors 2011, 4:195. BioMed Central Full Text
• [4]Neghina R, Dumitrascu V, Neghina AM, Vlad DC, Petrica L, Vermesan D, et al. Epidemiology of ascariasis, enterobiasis and giardiasis in a Romanian western county (Timis), 1993–2006. Acta Trop. 2013;125:98–101.
• [5]Dutto M, Montu D, Raineri G: Enterobiasis in pediatric subjects in north-western Italy: a study of home remedies. Ann Ig 2012, 24:81-4.
• [6]Remm M: Distribution of enterobiasis among nursery school children in SE Estonia and of other helminthiases in Estonia. Parasitol Res 2006, 99:729-36.
• [7]Gonzalez-Moreno O, Domingo L, Teixidor J, Gracenea M: Prevalence and associated factors of intestinal parasitisation: a cross-sectional study among outpatients with gastrointestinal symptoms in Catalonia, Spain. Parasitol Res 2011, 108:87-93.
• [8]Bethony J, Brooker S, Albonico M, Geiger SM, Loukas A, Diemert D, et al.: Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet 2006, 367:1521-32.
• [9]Song HJ, Cho CH, Kim JS, Choi MH, Hong ST: Prevalence and risk factors for enterobiasis among preschool children in a metropolitan city in Korea. Parasitol Res 2003, 91:46-50.
• [10]Li YL: Human parasitology. People's Medical Publishing House, Beijing; 2008.
• [11]Kim DH, Son HM, Kim JY, Cho MK, Park MK, Kang SY, et al.: Parents' knowledge about enterobiasis might be one of the most important risk factors for enterobiasis in children. Korean J Parasitol 2010, 48:121-6.
• [12]Zhao YE, Zhang H, Chang Y, Xun M, Wu XH: The relationship between the infection of pinworn and personal-social factors and its influence on the children's growth. Chin J Parasit Dis Con 2001, 14:268-71.
• [13]Serpytis M, Seinin D: Fatal case of ectopic enterobiasis: Enterobius vermicularis in the kidneys. Scand J Urol Nephrol 2012, 46:70-2.
• [14]Pampiglione S, Rivasi F: Enterobiasis in ectopic locations mimicking tumor-like lesions. Int J Microbiol 2009, 2009:642481.
• [15]Xu LQ, Chen YD, Sun FH, Cai N, Fang YY, Wang LP, et al.: A National Survey on Current Status of the Important Parasitic Diseases in Human Population. Chin J Parasitol Parasit Dis 2005, 23:332-9.
• [16]Zhang XC, Zhang QM, Pei FQ, Wang JL, Lin RX, Ruan CW: Survey on the infection situations of soil-borne nematodes in 5 surveillance sites at Guangdong Province in 2008–2009. J Trop Med 2010, 10:990-2.
• [17]Zhang QM, Zhang XC, Deng ZH, Lin RX, Wang JL, Ruan CW. Surveillance situations and analysis of soil-borne nematodiasis surveillance sites of Guangdong province in 2008. J Trop Med. 2011;11:703–5.
• [18]Nithikathkul C, Akarachantachote N, Wannapinyosheep S, Pumdonming W, Brodsky M, Sukthana Y: Impact of health educational programmes on the prevalence of enterobiasis in schoolchildren in Thailand. J Helminthol 2005, 79:61-5.
• [19]Chen YD, Wang JJ, Zhu HH, Zhu TJ, Zang W, Qian MB, et al.: Enterobius vermicularis Infection Status among Children in 9 Provinces/Autonomous Regions/Municipalities of China. Chin J Parasitol Parasit Dis 2013, 31:251-5.
• [20]Zhang QM, Fang YY, Zhang XC, Ruan CW, Su GH, Liu T: Analysis on the surveillance situations of the national soil transmitted nematodiasis surveillance site in Gaozhou city in 2007. J Trop Med 2008, 8:1176-7.
• [21]Yang YS, Kim SW, Jung SH, Huh S, Lee JH: Chemotherapeutic trial to control enterobiasis in school children. Korean J Parasitol 1997, 35:265-9.
• [22]Coulaud JP, Rossignol JF: Albendazole: a new single dose anthelmintic. Study in 1455 patients. Acta Trop 1984, 41:87-90.
• [23]St Georgiev V: Chemotherapy of enterobiasis (oxyuriasis). Expert Opin Pharmacother 2001, 2:267-75.
• [24]Kang IS, Kim DH, An HG, Son HM, Cho MK, Park MK, et al.: Impact of health education on the prevalence of enterobiasis in Korean preschool students. Acta Trop 2012, 122:59-63.
• [25]Otu-Bassey IB, Useh MF, Alaribe AA: The post-treatment effects of enterobiasis on the occurrence of enuresis among children in Calabar, Nigeria. Asian Pac J Trop Med 2011, 4:315-9.
• [26]Kim DH, Cho MK, Park MK, Kang SA, Kim BY, Park SK, et al.: Environmental factors related to enterobiasis in a southeast region of Korea. Korean J Parasitol 2013, 51:139-42.
• [27]Hong SH, Jeong YI, Lee JH, Cho SH, Lee WJ, Lee SE: Prevalence of Enterobius vermicularis among preschool children in Muan-gun, Jeollanam-do, Korea. Korean J Parasitol 2012, 50:259-62.
• [28]Salim N, Schindler T, Abdul U, Rothen J, Genton B, Lweno O, et al.: Enterobiasis and strongyloidiasis and associated co-infections and morbidity markers in infants, preschool- and school-aged children from rural coastal Tanzania: a cross-sectional study. BMC Infect Dis 2014, 14:644. BioMed Central Full Text