Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report

Journal of Medical Case Reports

Hakan Bozcuk¹  Mustafa Ozdogan¹  Burhan Savas¹  Hasan Senol Coskun¹  Sema Sezgin Goksu¹  Mukremin Uysal¹ 

[1] Department of Medical Oncology, Akdeniz University Faculty of Medicine, Antalya, Turkey

关键词: Intaarticular hemorrhage;    Synovial metastasis;    Colorectal cancer;    Bevacizumab;   

Others  :  1195678
DOI  :  10.1186/1752-1947-6-188

 received in 2011-10-28, accepted in 2012-05-11,  发布年份 2012

【 摘 要 】

Introduction

Bevacizumab is a monoclonal antibody against vascular endothelial growth factor. It is widely used in the treatment of metastatic colorectal cancer. It has some specific side effects including severe bleeding, wound healing problems, gastrointestinal perforation, proteinuria and hypertension.

Case presentation

We present the case of a 65-year old Asian man with synovial metastasis of the knee who experienced intraarticular hemorrhage after bevacizumab treatment. He presented with monoarthritis of the left knee.

Conclusion

Bevacizumab-related hemorrhage can cause serious morbidity and unusual sites of hemorrhage may be seen.

【 授权许可】

   
2012 Uysal et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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