Non-alcoholic fatty liver disease (NAFLD): a tale of fat and sugar?

Fibrogenesis & Tissue Repair

Lisa Longato¹ 

[1] UCL Institute for Liver and Digestive Health, Royal Free Hospital, U3rd Floor, Rowland Hill Street, London NW3 2PF, UK

关键词: Western diet;    Rats;    Non-alcoholic steatohepatitis;    NAFLD;    Mice;    High-fructose corn syrup;    High-fat diet;    Fructose;   

Others  :  803097
DOI  :  10.1186/1755-1536-6-14

 received in 2013-06-04, accepted in 2013-06-14,  发布年份 2013

【 摘 要 】

The global diffusion of the so-called Western diet, which is enriched in fat and carbohydrates, such as fructose, has been proposed to be an underlying cause of the increased prevalence of metabolic conditions, including non-alcoholic fatty liver disease (NAFLD). This Smart Card summarizes the main metabolic and hepatic histological features of rodent models fed with diets combining high fat and fructose.

【 授权许可】

   
2013 Longato; licensee BioMed Central Ltd.

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