Risk factors associated with asbestos-related diseases: a community-based case–control study

BMC Public Health

Jaume Canela-Soler⁸  Ramon Orriols Martínez¹  Isidre Grimau Malet⁴  Ilona Krier Günther⁵  Xavier Martinez Artés⁶  Isabel García Allas²  Constança Alberti-Casas³  Josep Tarrés Olivella⁷  Rafael Abós-Herràndiz⁵  Magdalena-Isabel Rosell-Murphy⁶ 

[1] Respiratory Medicine Department, University Hospital Vall d'Hebron - CIBER Respiratory Diseases (CIBERES), Catalan Institute of Health, Barcelona, Spain;Primary Care Team Rosa dels Vents, Catalan Institute of Health, Barberà del Vallès, Spain;ICAM, Department of Health Evaluation, Barcelona, Spain;Palliative Care Unit, Consorci Hospitalari Parc Taulí, Sabadell, Spain;Primary Care Team Pinetons, Catalan Institute of Health, Ripollet, Spain;Primary Care Team Serraparera, Catalan Institute of Health, Cerdanyola del Vallès, Spain;Primary Care Team Canaletes, Catalan Institute of Health, Cerdanyola del Vallès, Spain;Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, USA

关键词: Case–control study;    Mesothelioma;    Primary health care;    Asbestos-related diseases;   

Others  :  1161959
DOI  :  10.1186/1471-2458-13-723

 received in 2013-04-25, accepted in 2013-08-01,  发布年份 2013

【 摘 要 】

Background

Asbestos is a first level carcinogen. However, few epidemiological studies analyse the risk and protective factors associated with asbestos-related diseases and follow up these conditions in the general population. Pleural mesothelioma, caused by inhalation of asbestos fibres at work, at home or in the environment, is the most representative asbestos-related disease.

The objectives of this study are to analyse the risk and protective factors associated with asbestos-related diseases and to investigate the incidence of new clinical manifestations in patients already diagnosed with some form of ARD.

Methods/Design

We have designed a matched case–control study with follow up of both cohorts from a population of a health district of the Barcelona province that has been exposed to asbestos for a period of 90 years.

Discussion

A better understanding of asbestos-related diseases should improve i) the clinical and epidemiological follow up of patients with this condition; ii) the design of new treatment strategies; iii) and the development of preventive activities. At the end of the study, the two cohorts created in this study (affected cases and healthy controls) will constitute the basis for future research.

【 授权许可】

   
2013 Rosell-Murphy et al.; licensee BioMed Central Ltd.

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