Antimicrobial potential of 27 plants consumed by chimpanzees (Pan troglodytes verus Blumenbach) in Ivory Coast

BMC Complementary and Alternative Medicine

Mamidou Witabouna Koné¹  Bassirou Bonfoh¹  Amoin Georgette Konan²  Angora Rémi Constant Ahoua¹ 

[1] Centre Suisse de Recherches Scientifiques en Côte d’Ivoire, Abidjan, BP 1303 Abidjan 01, Côte d’Ivoire;Laboratoire de Biochimie et Science des aliments, Unité de Formation et de Recherche des Biosciences, Université Félix Houphouët-Boigny, Abidjan, BP 582 Abidjan 22, Côte d’Ivoire

关键词: Ivory Coast;    Tristemma coronatum;    Beilschmiedia mannii;    Yeast;    Bacteria;    Antimicrobial;    Chimpanzee’s diet;   

Others  :  1233219
DOI  :  10.1186/s12906-015-0918-7

 received in 2015-08-29, accepted in 2015-10-14,  发布年份 2015

【 摘 要 】

Background

Due to their genetic proximity, chimpanzees share with human several diseases including bacterial, fungal and viral infections, such as candidiasis, acquired immune deficiency syndrome (AIDS), Ebola virus disease. However, in its natural environment, chimpanzees are tolerant to several pathogens including simian immunodeficiency virus (SIV), virus related to human immunodeficiency virus (HIV) that contribute to the emergence of opportunistic diseases such as microbial infections.

Methods

Twenty seven species of plants consumed by chimpanzees were evaluated for their antimicrobial potential against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans, Candida tropicalis and Candida glabrata using the agar diffusion technique and micro-dilution in 96-well plates. In total 132 extracts (33 dichloromethane, 33 methanol, 33 ethyl acetate and 33 aqueous) were tested.

Results

The results showed that 24 extracts (18 %) showed activity against bacteria and 6 extracts (5 %) were active against yeasts. The minimal inhibitory concentrations (MICs) values of active extracts ranged between 23 and 750 μg/ml for bacteria and between 188 and 1500 μg/ml for yeasts.

Conclusion

Tristemma coronatum was the most promising on the studied microorganisms followed by Beilschmiedia mannii. The extracts of the two plants indicated by chimpanzees have potential for antimicrobial use in human.

【 授权许可】

   
2015 Ahoua et al.

【 图 表 】

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【 参考文献 】

• [1]Diallo A. Etude de la phytochimie et des activités biologiques de Syzygium guineense Willd. (Myrtaceae). Faculté de Médecine, de Pharmacie et d’Odoto-Stomatologie, Université de Bamako, Mali; 2005.
• [2]Blythe S. An introduction to medicines from plants. 1999. http://www. rainforesteducation.com/medicines/PlantMedicines/rfmedicines.htm. Accessed 24 Mars 2015
• [3]Chanda S, Rakholiya K. Combination therapy: Synergism between natural plant extracts and antibiotics against infectious diseases. In: Science against microbiology pathogens: communicating current research and technological advances. 2011.520-9.
• [4]Soro D, Kone MW, Kamanzi K. Evaluation des activités antimicrobiennes et anti-radicaux libres de quelques taxons bioactifs de Côte d’Ivoire. Eur J Sci Res. 2010; 40:307-17.
• [5]Akinyemi KO, Oladapo O, Okwara CE, Ibe CC, Fasure KA. Screening of crude extracts of six medicinal plants used in South-West Nigerian unorthodox medicine for anti-methicillin resistant Staphylococcus aureus activity. BMC Complement Altern Med. 2005; 5:6. BioMed Central Full Text
• [6]Akoua-Koffi C, Guessennd N, Gbonon V, Faye-Ketté H, Dosso M. Methicillin-resistance of Staphylococcus aureus in Abidjan (1998–2001): a new hospital problem. Med Mal Infect. 2004; 34:132-6.
• [7]Balkis MM, Leidich SD, Mukherjee PK, Ghannoum MA. Mechanisms of fungal resistance: an overview. Drugs. 2002; 62:1025-40.
• [8]Benbachir M, Benredjeb S, Boye CS, Dosso M, Belabbes H, Kamoun A et al.. Two-year surveillance of antibiotic resistance in Streptococcus pneumoniae in four African cities. Antimicrob Agents Chemother. 2001; 45:627-9.
• [9]Ju J, Polhamus C, Marr K, Holland S, Bennett JE. Efficacies of fluconazole, caspofungin, and amphotericin B in Candida glabrata-infected p47phox−/−knockout mice. Antimicrob Agents Chemother. 2002; 46:1240-5.
• [10]Kacou-N’Douba A, Bouzid SA, Guessennd KN, Kouassi-M’Bengue AA, Faye-Kette AY, Dosso M. Antimicrobial resistance of nasopharyngeal isolates of Streptococcus pneumoniae in healthy carriers: report of a study in 5-year-olds in Marcory, Abidjan, Côte d’Ivoire. Ann Trop Paediatr. 2001; 21:149-54.
• [11]Ramage G, Bachmann S, Patterson T, Wickes B, López-Ribot J. Investigation of multidrug efflux pumps in relation to fluconazole resistance in Candida albicans biofilms. J Antimicrob Chemother. 2002; 49:973-80.
• [12]Rodero L, Cuenca-Estrella M, Cordoba S, Cahn P, Davel G, Kaufman S et al.. Transient fungemia caused by an amphotericin B-resistant isolate of Candida haemulonii. J Clin Microbiol. 2002; 40:2266-9.
• [13]Premier rapport de l’OMS sur la résistance aux antibiotiques: une menace grave d’ampleur mondiale. 2014. http://www. who.int/mediacentre/news/releases/2014/amr-report/fr/. Accessed 16 Nov 2014
• [14]WHO. Antimicrobial resistance: Global Report on surveillance 2014. WHO Press. 2014. http://www.who.int/mediacentre/news/releases/2014/amr-report/fr/. Accessed 30 Oct 2014.
• [15]Guessennd N, Gbonon V, Tiékoura K, Kakou-N’douba A, Ouattara D, Boni-Cissé C et al.. Evolution de la résistance bactérienne à l’imipénème en Côte d’Ivoire de 2005 à 2009. 2009.
• [16]Senhaji O, Faid M, Elyachioui M, Dehhaoui M. Étude de l’activité antifongique de divers extraits de cannelle. J Mycol Med. 2005; 15:220-9.
• [17]Atindehou K, Koné M, Terreaux C, Traoré D, Hostettmann K, Dosso M. Evaluation of the antimicrobial potential of medicinal plants from the Ivory Coast. Phytother Res. 2002; 16:497-502.
• [18]Koné WM, Atindéhou KK, Terreaux C, Hostettmann K, Traore D, Dosso M. Traditional medicine in North Cote-d’Ivoire: screening of 50 medicinal plants for antibacterial activity. J Ethnopharmacol. 2004; 93:43-9.
• [19]Kouadio F, Guessennd N, Karamoko O, Bahi C, Adama C, Dosso M. Action antibactérienne de l’extrait éthanolique 70 % de Clerodendrum splendens (G. Don) (Verbenacae) sur des souches bactériennes isolées de selles chez des enfants diarrhéiques. Inter J Biol Chem Sci. 2013; 7:1332-7.
• [20]Tra Bi FH, Koné MW, Kouamé NF. Antifungal activity of Erigeron floribundus (Asteraceae) from Côte d’Ivoire, West Africa. Trop J Pharm Res. 2008; 7:975-9.
• [21]Sibley CG, Ahlquist JE. The phylogeny of the hominoid primates, as indicated by DNA-DNA hybridization. J Mol Evol. 1984; 20:2-15.
• [22]Kurth R, Norley S. Why don’t the natural hosts of SIV develop simian AIDS? J NIH Res. 1996; 8:33-7.
• [23]Weiss RA. Gulliver’s travels in HIVland. Nature. 2001; 410:963-7.
• [24]Gas V. SIDA: pourquoi les singes résistent au VIH? 2004. http://www. rfi.fr/actufr/articles/052/article_27358.asp. Accessed 30 Oct 2014
• [25]Maladies opportunistes liées au VIH : Actualisation ONUSIDA. Collection Meilleures Pratiques de l’ONUSIDA. 1999. http://data. unaids.org/publications/irc-pub05/opportu_fr.pdf. Accessed 28 Sept 2014
• [26]Ahoua ARC, Koné MW, Konan AG, Tra Bi FH, Bonfoh B. Antioxidant activity of eight plants consumed by great apes in Côte d’Ivoire. Afr J Biotechnol. 2012; 11:11732-40.
• [27]Winding W. One Health, pulling animal health and public health together. 2007. http://www. fve.org/news/presentations/one_health_concept.ppt. Accessed 31 Oct 2014
• [28]Zinsstag J, Schelling E, Roth F, Bonfoh B, de Savigny D, Tanner M. Human benefits of animal interventions for zoonosis control. Emerg Infect Dis. 2007; 13:527-31.
• [29]Zinsstag J, Schelling E, Wyss K, Mahamat MB. Potential of cooperation between human and animal health to strengthen health systems. Lancet. 2005; 366:2142-5.
• [30]N’Guessan KA. Aspects quantitatifs et qualitatifs du régime alimentaire des chimpanzés (Pan Troglodytes Verus, Blumenbach 1779) au Parc National De Taï, Côte D’Ivoire. UFR Biosciences, Université Félix Houphouët-Boigny–Cocody, Abidjan Côte d’Ivoire; 2012.
• [31]Kamanzi A. Plantes médicinales de Côte d’Ivoire: investigations phytochimiques guidées par des essais biologiques. UFR Biosciences, Université de Cocody-Abidjan (Côte d’Ivoire); 2002.
• [32]Rakotoniriana EF, Rajaonarison JF, Raoelison EG, Rajaonarivelo JP, Manga N, Solofoniaina M et al.. Antimicrobial activity of 23 endemic plants in Madagascar. Trop J Pharm Res. 2010; 9:165-71.
• [33]Statistica pour Windows, release 5.5. Statoft Inc, France; 1999.
• [34]Yao K, Koné M, Bonfoh B, Kamanzi K. Antioxidant activity and total phenolic content of nine plants from Côte d’Ivoire (West Africa). J Appl Pharm Sci. 2014; 4:36-41.
• [35]Fankam AG, Kuiate JR, Kuete V. Antibacterial activities of Beilschmiedia obscura and six other Cameroonian medicinal plants against multi-drug resistant Gram-negative phenotypes. BMC Complement Altern Med. 2014; 14:241. BioMed Central Full Text
• [36]Chouna JR, Nkeng-Efouet PA, Lenta BN, Devkota KP, Neumann B, Stammler H-G et al.. Antibacterial endiandric acid derivatives from Beilschmiedia anacardioides. Phytochemistry. 2009; 70:684-8.
• [37]Paulo Mde Q, Barbosa-Filho J, Lima E, Maia R, Barbosa Rde C, Kaplan M. Antimicrobial activity of benzylisoquinoline alkaloids from Annona salzmanii D.C. J Ethnopharmacol. 1992; 36:39-41.
• [38]Fitzgerald DJ, Stratford M, Gasson MJ, Narbad A. Structure-function analysis of the vanillin molecule and its antifungal properties. J Agric Food Chem. 2005; 53:1769-75.
• [39]Lenta BN, Tantangmo F, Devkota KP, Wansi JD, Chouna JR, Soh RC et al.. Bioactive constituents of the stem bark of Beilschmiedia zenkeri. J Nat Prod. 2009; 72:2130-4.
• [40]Park J, Lee J, Jung E, Park Y, Kim K, Park B et al.. In vitro antibacterial and anti-inflammatory effects of honokiol and magnolol against Propionibacterium sp. Eur J Pharmacol. 2004; 496:189-95.
• [41]Sugiyama Y, Koman J. A preliminary list of chimpanzees’ alimentation at Bossou, Guinea. Primates. 1987; 28:133-47.
• [42]Kouamé N, Gnahoua G, Kouassi KE, Traore D. Plantes alimentaires spontanées de la région du Fromager (Centre-Ouest de la Côte d’Ivoire): flore, habitats et organes consommés. Sci Nat. 2008; 5:61-70.
• [43]Wansi JD, Chiozem DD, Tcho AT, Toze FAA, Devkota KP, Ndjakou BL et al.. Antimicrobial and antioxidant effects of phenolic constituents from Klainedoxa gabonensis. Pharm Biol. 2010; 48:1124-9.
• [44]Bouquet A. Traditional doctors and traditional medicines of Congo Brazzaville. Orstom, Paris; 1969.
• [45]Onanga M, Ekouya A, Ouabonzi A, Itoua GB. Ethnobotanical, pharmacological and chemical studies of plants used in the treatment of ‘Mwandza’dermatites. Fitoterapia. 1999; 70:579-85.