Antimicrobial potential of 27 plants consumed by chimpanzees (Pan troglodytes verus Blumenbach) in Ivory Coast

BMC Complementary and Alternative Medicine

Research Article

Bassirou Bonfoh¹  Amoin Georgette Konan²  Mamidou Witabouna Koné³  Angora Rémi Constant Ahoua³ 

[1] Centre Suisse de Recherches Scientifiques en Côte d’Ivoire, BP 1303 Abidjan 01, Abidjan, Côte d’Ivoire;Centre Suisse de Recherches Scientifiques en Côte d’Ivoire, BP 1303 Abidjan 01, Abidjan, Côte d’Ivoire;Laboratoire de Biochimie et Science des aliments, Unité de Formation et de Recherche des Biosciences, Université Félix Houphouët-Boigny, BP 582 Abidjan 22, Abidjan, Côte d’Ivoire;Unité de Formation et de Recherche des Sciences de la Nature, Université Nangui Abrogoua, BP 801 Abidjan 02, Abidjan, Côte d’Ivoire;Centre Suisse de Recherches Scientifiques en Côte d’Ivoire, BP 1303 Abidjan 01, Abidjan, Côte d’Ivoire;

关键词: Chimpanzee’s diet;    Antimicrobial;    Bacteria;    Yeast;    Beilschmiedia mannii;    Tristemma coronatum;    Ivory Coast;   

DOI  :  10.1186/s12906-015-0918-7

 received in 2015-08-29, accepted in 2015-10-14,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundDue to their genetic proximity, chimpanzees share with human several diseases including bacterial, fungal and viral infections, such as candidiasis, acquired immune deficiency syndrome (AIDS), Ebola virus disease. However, in its natural environment, chimpanzees are tolerant to several pathogens including simian immunodeficiency virus (SIV), virus related to human immunodeficiency virus (HIV) that contribute to the emergence of opportunistic diseases such as microbial infections.MethodsTwenty seven species of plants consumed by chimpanzees were evaluated for their antimicrobial potential against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans, Candida tropicalis and Candida glabrata using the agar diffusion technique and micro-dilution in 96-well plates. In total 132 extracts (33 dichloromethane, 33 methanol, 33 ethyl acetate and 33 aqueous) were tested.ResultsThe results showed that 24 extracts (18 %) showed activity against bacteria and 6 extracts (5 %) were active against yeasts. The minimal inhibitory concentrations (MICs) values of active extracts ranged between 23 and 750 μg/ml for bacteria and between 188 and 1500 μg/ml for yeasts.ConclusionTristemma coronatum was the most promising on the studied microorganisms followed by Beilschmiedia mannii. The extracts of the two plants indicated by chimpanzees have potential for antimicrobial use in human.

【 授权许可】

CC BY   
© Ahoua et al. 2015