VANTED v2: a framework for systems biology applications

BMC Systems Biology

Falk Schreiber²  Christian Klukas¹  Tobias Czauderna¹  Matthias Klapperstück¹  Hendrik Treutler¹  Eva Grafahrend-Belau¹  Anja Hartmann¹  Astrid Junker¹  Hendrik Rohn¹ 

[1] , Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Corrensstr. 3, 06466 Gatersleben, Germany;Clayton School of Information Technology, Monash University, Victoria 3800, Australia

关键词: Model simulation;    -Omics;    Data analysis;    Data integration;    Data visualization;    Biological networks;   

Others  :  1143462
DOI  :  10.1186/1752-0509-6-139

 received in 2012-07-26, accepted in 2012-11-01,  发布年份 2012

【 摘 要 】

Background

Experimental datasets are becoming larger and increasingly complex, spanning different data domains, thereby expanding the requirements for respective tool support for their analysis. Networks provide a basis for the integration, analysis and visualization of multi-omics experimental datasets.

Results

Here we present VANTED (version 2), a framework for systems biology applications, which comprises a comprehensive set of seven main tasks. These range from network reconstruction, data visualization, integration of various data types, network simulation to data exploration combined with a manifold support of systems biology standards for visualization and data exchange. The offered set of functionalities is instantiated by combining several tasks in order to enable users to view and explore a comprehensive dataset from different perspectives. We describe the system as well as an exemplary workflow.

Conclusions

VANTED is a stand-alone framework which supports scientists during the data analysis and interpretation phase. It is available as a Java open source tool from http://www.vanted.org. webcite

【 授权许可】

   
2012 Rohn et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 2.

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