期刊论文详细信息
BMC Musculoskeletal Disorders
Mortality and complications of hip fracture in young adults: a nationwide population-based cohort study
Tsai-Hsueh Leu3  Hsi-Chin Wu1  Yu-Jun Chang2  Chang-Bi Wang4  Chi-Fung Cheng4  Wen-Miin Liang4  Chi Lo5  Cheng-Chun Wu3  Jeff Chien-Fu Lin3 
[1] School of Medicine, China Medical University, Taichung 40402, Taiwan;Epidemiology and Biostatistics Center, Changhua Christian Hospital, Changhua 50006, Taiwan;Department of Orthopedic Surgery, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan;Department of Public Health, China Medical University, Taichung 40402, Taiwan;Department of Hospitality Management, Chung Hua University, Hsinchu 30012, Taiwan
关键词: Mortality;    Complication;    Hip fracture;   
Others  :  1118380
DOI  :  10.1186/1471-2474-15-362
 received in 2014-01-27, accepted in 2014-10-20,  发布年份 2014
PDF
【 摘 要 】

Background

This study assessed the mortality and complications of hip fractures using in-patients aged 20–40 years from a nationwide population database in Taiwan.

Methods

Subjects were selected from Taiwan’s National Health Insurance Research Database for the period 2000–2008, and these subjects were followed up until the end of 2010. A total of 5,079 (3,879 male and 1,200 female) subjects were admitted for the first time with primary diagnosis of hip fracture and treated with operation. We calculated the long-term overall survival rate and complication-free rate. We also assessed the risk factors for mortality and complications.

Results

The 1-month, 3-month, 6-month, 1-year, 2-year, 5-year, and 10-year complication-free rates were 98.3%, 96.2%, 94.5%, 86.8%, 80.4%, 75.3%, and 73.5% for the entire cohort, respectively. The 10-year survival rates were 93.3%, 91.8%, and 94.5% for total cases, trochanteric fracture, and cervical fracture, respectively. The 10-year complication-free rates were 73.5%, 80.5%, and 67.3% for total cases, trochanteric fracture, and cervical fracture, respectively. The risk factors for overall death were male, older age, and greater number of Charlson comorbidity index (CCI) comorbidities. The risk factors for complication were cervical fracture, and greater number of CCI comorbidities. Complications resulted in 42.83% of patients receiving internal fixation implants or prothesis removal and 2.01% underwent conversion to revision arthroplasty during follow-up.

Conclusions

The overall 10-year survival rate in hip fracture patients aged 20–40 years in Taiwan was over 90%. The 10-year complication-free rates were around 70%. Preventing the occurrence of severe complications after hip fracture among young adults is an important public health issue that warrants greater attention.

【 授权许可】

   
2014 Lin et al.; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20150206023315798.pdf 335KB PDF download
Figure 1. 64KB Image download
【 图 表 】

Figure 1.

【 参考文献 】
  • [1]Zuckerman JD: Hip fracture. N Engl J Med 1996, 334(23):1519-1525.
  • [2]Wolinsky FD, Fitzgerald JF, Stump TE: The effect of hip fracture on mortality, hospitalization, and functional status: a prospective study. Am J Public Health 1997, 87(3):398-403.
  • [3]Cummings SR, Melton LJ: Epidemiology and outcomes of osteoporotic fractures. Lancet 2002, 359(9319):1761-1767.
  • [4]Farahmand BY, Michaelsson K, Ahlbom A, Ljunghall S, Baron JA, Swedish Hip Fracture Study G: Survival after hip fracture. OsteoporosInt 2005, 16(12):1583-1590.
  • [5]Court-Brown CM, Caesar B: Epidemiology of adult fractures: A review. Injury 2006, 37(8):691-697.
  • [6]Abrahamsen B, Van Staa T, Ariely R, Olson M, Cooper C: Excess mortality following hip fracture: a systematic epidemiological review. OsteoporosInt 2009, 20(10):1633-1650.
  • [7]Haentjens P, Magaziner J, Colon-Emeric CS, Vanderschueren D, Milisen K, Velkeniers B, Boonen S: Meta-analysis: excess mortality after hip fracture among older women and men. Ann Intern Med 2010, 152(6):380-390.
  • [8]Wu TY, Jen MH, Bottle A, Liaw CK, Aylin P, Majeed A: Admission rates and in-hospital mortality for hip fractures in England 1998 to 2009: time trends study. J Public Health 2011, 33(2):284-291.
  • [9]Kim SH, Meehan JP, Blumenfeld T, Szabo RM: Hip fractures in the United States: 2008 nationwide emergency department sample. Arthritis Care Res (Hoboken) 2012, 64(5):751-757.
  • [10]Protzman RR, Burkhalter WE: Femoral-neck fractures in young adults. J Bone Joint Surg Am Vol 1976, 58(5):689-695.
  • [11]Askin SR, Bryan RS: Femoral neck fractures in young adults. ClinOrthopRelat Res 1976, 114:259-264.
  • [12]Swiontkowski MF, Winquist RA, Hansen ST Jr: Fractures of the femoral neck in patients between the ages of twelve and forty-nine years. J Bone Joint Surg Am Vol 1984, 66(6):837-846.
  • [13]Robinson CM, Court-Brown CM, McQueen MM, Christie J: Hip fractures in adults younger than 50 years of age. Epidemiology and results. ClinOrthopRelat Res 1995, 312:238-246.
  • [14]Hwang LC, Lo WH, Chen WM, Lin CF, Huang CK, Chen CM: Intertrochanteric fractures in adults younger than 40 years of age. Arch Orthop Trauma Surg 2001, 121(3):123-126.
  • [15]Verettas DA, Galanis B, Kazakos K, Hatziyiannakis A, Kotsios E: Fractures of the proximal part of the femur in patients under 50 years of age. Injury 2002, 33(1):41-45.
  • [16]Platzer P, Thalhammer G, Wozasek GE, Vecsei V: Femoral shortening after surgical treatment of trochanteric fractures in nongeriatric patients. J Trauma 2008, 64(4):982-989.
  • [17]Karantana A, Boulton C, Bouliotis G, Shu KS, Scammell BE, Moran CG: Epidemiology and outcome of fracture of the hip in women aged 65 years and under: a cohort study. J Bone Joint Surg Br Vol 2011, 93(5):658-664.
  • [18]Min BW, Kim SJ: Avascular necrosis of the femoral head after osteosynthesis of femoral neck fracture. Orthopedics 2011, 34(5):349.
  • [19]Duckworth AD, Bennet SJ, Aderinto J, Keating JF: Fixation of intracapsular fractures of the femoral neck in young patients: risk factors for failure. J Bone Joint Surg Br Vol 2011, 93(6):811-816.
  • [20]Charlson ME, Pompei P, Ales KL, MacKenzie CR: A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987, 40(5):373-383.
  • [21]Lu-Yao GL, Baron JA, Barrett JA, Fisher ES: Treatment and survival among elderly Americans with hip fractures: a population-based study. Am J Public Health 1994, 84(8):1287-1291.
  • [22]Muraki S, Yamamoto S, Ishibashi H, Nakamura K: Factors associated with mortality following hip fracture in Japan. J Bone Miner Metab 2006, 24(2):100-104.
  • [23]Haentjens P, Autier P, Barette M, Venken K, Vanderschueren D, Boonen S, Hip Fracture Study G: Survival and functional outcome according to hip fracture type: a one-year prospective cohort study in elderly women with an intertrochanteric or femoral neck fracture. Bone 2007, 41(6):958-964.
  • [24]Holt G, Smith R, Duncan K, Finlayson DF, Gregori A: Early mortality after surgical fixation of hip fractures in the elderly: an analysis of data from the scottish hip fracture audit. J Bone Joint Surg Br Vol 2008, 90(10):1357-1363.
  • [25]Lin WP, Wen CJ, Jiang CC, Hou SM, Chen CY, Lin J: Risk factors for hip fracture sites and mortality in older adults. J Trauma 2011, 71(1):191-197.
  • [26]Kesmezacar H, Ayhan E, Unlu MC, Seker A, Karaca S: Predictors of mortality in elderly patients with an intertrochanteric or a femoral neck fracture. J Trauma 2010, 68(1):153-158.
  • [27]Castronuovo E, Pezzotti P, Franzo A, DiLallo D, Guasticchi G: Early and late mortality in elderly patients after hip fracture: a cohort study using administrative health databases in the Lazio region, Italy. BMC Geriatr 2011, 11:37. BioMed Central Full Text
  • [28]Kim SM, Moon YW, Lim SJ, Yoon BK, Min YK, Lee DY, Park YS: Prediction of survival, second fracture, and functional recovery following the first hip fracture surgery in elderly patients. Bone 2012, 50(6):1343-1350.
  • [29]Gao H, Liu Z, Xing D, Gong M: Which is the best alternative for displaced femoral neck fractures in the elderly?: A meta-analysis. ClinOrthopRelat Res 2012, 470(6):1782-1791.
  • [30]Wang J, Jiang B, Marshall RJ, Zhang P: Arthroplasty or internal fixation for displaced femoral neck fractures: which is the optimal alternative for elderly patients? A meta-analysis. IntOrthop 2009, 33(5):1179-1187.
  • [31]Bhandari M, Devereaux PJ, Swiontkowski MF, Tornetta P 3rd, Obremskey W, Koval KJ, Nork S, Sprague S, Schemitsch EH, Guyatt GH: Internal fixation compared with arthroplasty for displaced fractures of the femoral neck. A meta-analysis. J Bone Joint Surg Am Vol 2003, 85-A(9):1673-1681.
  • [32]Dignam JJ, Kocherginsky MN: Choice and interpretation of statistical tests used when competing risks are present. J ClinOncol 2008, 26(24):4027-4034.
  • [33]Radley DC, Gottlieb DJ, Fisher ES, Tosteson AN: Comorbidity risk-adjustment strategies are comparable among persons with hip fracture. J ClinEpidemiol 2008, 61(6):580-587.
  • [34]Kirkland LL, Kashiwagi DT, Burton MC, Cha S, Varkey P: The Charlson Comorbidity Index Score as a predictor of 30-day mortality after hip fracture surgery. Am J Med Qual 2011, 26(6):461-467.
  文献评价指标  
  下载次数:33次 浏览次数:20次