Aboriginal birth cohort (ABC): a prospective cohort study of early life determinants of adiposity and associated risk factors among Aboriginal people in Canada

BMC Public Health

Sonia S Anand²  Koon K Teo⁴  Katherine M Morrison⁴  Sarah McDonald¹  Rebecca Anglin¹  Ruby Miller³  Julie Wilson³  Gita Wahi¹ 

[1] McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada;Population Genomics Program, Chanchlani Research Centre, McMaster University, Hamilton, Canada;Six Nations Health Services, 1745 Chiefswood Rd, Ohsweken, ON N0A 1M0, Canada;Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Canada

关键词: Adiposity;    Early origins;    Birth cohort;    Aboriginal;   

Others  :  1162074
DOI  :  10.1186/1471-2458-13-608

 received in 2013-04-15, accepted in 2013-06-19,  发布年份 2013

【 摘 要 】

Background

Aboriginal people living in Canada have a high prevalence of obesity, type 2 diabetes, and cardiovascular disease (CVD). To better understand the pre and postnatal influences on the development of adiposity and related cardio-metabolic factors in adult Aboriginal people, we will recruit and follow prospectively Aboriginal pregnant mothers and their children – the Aboriginal Birth Cohort (ABC) study.

Methods/design

We aim to recruit 300 Aboriginal pregnant mothers and their newborns from the Six Nations Reserve, and follow them prospectively to age 3 years. Key details of environment and health including maternal nutrition, glucose tolerance, physical activity, and weight gain will be collected. At birth, cord blood and placenta samples will be collected, as well as newborn anthropometric measurements. Mothers and offspring will be followed annually with serial measurements of diet and physical activity, growth trajectory, and adiposity.

Discussion

There is an urgent need to understand maternal and child factors that underlie the early development of adiposity and type 2 diabetes in Aboriginal people. The information generated from this cohort will assist the Six Nations community in developing interventions to prevent early adiposity in Aboriginal children.

【 授权许可】

   
2013 Wahi et al.; licensee BioMed Central Ltd.

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