Understanding barriers to optimal medication management for those requiring long-term dialysis: rationale and design for an observational study, and a quantitative description of study variables and data

BMC Nephrology

Mark R Marshall³  Julia Kennedy⁵  Jun S Suh⁷  Angela L Kam⁴  Porsche Tiavale²  Olita Taule’alo²  Krenare Pireva²  Sophia Lee²  Dharni Kumar²  Samantha Curd²  Edwin Rajah⁶  Tian M Ma⁷  Martin J Wolley¹  Trudi Aspden⁵ 

[1] School of Medicine, University of Queensland, 288 Herston Road, Brisbane 4006, Australia;Formerly of the School of Pharmacy, Faculty of Medical and Health Sciences, The University of Auckland, 85 Park Rd, Auckland 1142, New Zealand;School of Medicine, Faculty of Medical and Health Sciences, The University of Auckland, 85 Park Rd, Auckland 1142, New Zealand;Pharmacy Services, Counties Manukau District Health Board, Hospital Road, Otahuhu, Auckland 1640, New Zealand;School of Pharmacy, Faculty of Medical and Health Sciences, The University of Auckland, 85 Park Rd, Auckland 1142, New Zealand;Marketing Department, Faculty of Business, Auckland University of Technology, 46 Wakefield St, Auckland 1010, New Zealand;Department of Renal Medicine, Counties Manukau District Health Board, Hospital Road, Otahuhu, Auckland 1640, New Zealand

关键词: Illness perception;    Beliefs about medications;    Medication knowledge;    Health literacy;    Dialysis;    Medication adherence;   

Others  :  1220013
DOI  :  10.1186/s12882-015-0097-2

 received in 2014-10-20, accepted in 2015-06-25,  发布年份 2015

【 摘 要 】

Background

Rates of medication non-adherence in dialysis patients are high, and improving adherence is likely to improve outcomes. Few data are available regarding factors associated with medication adherence in dialysis patients, and these data are needed to inform effective intervention strategies.

Methods/design

This is an observational cross-sectional study of a multi-ethnic dialysis cohort from New Zealand, with the main data collection tool being an interviewer-assisted survey. A total of 100 participants were randomly sampled from a single centre, with selection stratified by ethnicity and dialysis modality (facility versus home). The main outcome measure is self-reported medication adherence using the Morisky 8-Item Medication Adherence Scale (MMAS-8). Study data include demographic, clinical, social and psychometric characteristics, the latter being constructs of health literacy, medication knowledge, beliefs about medications, and illness perceptions. Psychometric constructs were assessed through the following survey instruments; health literacy screening questions, the Medication Knowledge Evaluation Tool (Okuyan et al.), the Beliefs about Medication Questionnaire (Horne et al.), the Brief Illness Perception Questionnaire (Broadbent et al.). Using the study data, reliability analysis for internal consistency is satisfactory for the scales evaluating health literacy, medication knowledge, and beliefs about medications, with Chronbach’s α > 0.7 for all. Reliability analysis indicated poor internal consistency for scales relating to illness perceptions. MMAS-8 and all psychometric scores are normally distributed in the study data.

Discussion

This study will provide important information on the factors involved in medication non-adherence in New Zealand dialysis patients. The resulting knowledge will inform long-term initiatives to reduce medication non-adherence in dialysis patients, and help ensure that they are addressing appropriate and evidence based targets for intervention.

【 授权许可】

   
2015 Aspden et al.

【 图 表 】

Fig. 1.

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