Compression neuropathy caused by cancer metastasis to the optic nerve canal

BMC Research Notes

Nobuo Fuse²  Teiji Tominaga⁵  Norio Narita⁴  Kensuke Murakami⁵  Kazuyuki Ishida¹  Hiroshi Tamai³ 

[1] Department of Neurosurgery, Kesennuma City Hospital, 184 Tanaka, Kesennuma, Miyagi 988-0052, Japan;Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8573, Japan;Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan;Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan;Department of Pathology, Tohoku University Hospital, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan

关键词: Optic canal;    Metastasis;    Cancer;   

Others  :  1135153
DOI  :  10.1186/1756-0500-6-546

 received in 2012-11-29, accepted in 2013-12-18,  发布年份 2013

【 摘 要 】

Background

Cancerous cells are known to metastasize to different ocular structures. This happens especially to the choroid in males with lung cancer and females with breast cancer. However, we observed two cases of cancerous metastasis to the optic canal region. Both cases showed only a progressive decrease in vision without any other remarkable ophthalmological symptoms or abnormalities in the affected eye.

Case presentation

Two females, a 60-year-old and a 73-year-old, came to our hospital because of progressive loss of vision. These patients showed no remarkable symptoms or signs in their eyes except visual acuity loss. Several ophthalmoscopic examinations, such as slit lamp microscopy and fundoscopy, showed no abnormal changes in their affected eye but magnetic resonance imaging indicated a massive legion around the optic nerve.

Conclusion

It is possible for cancer to metastasize to the optic canal region and the existence of primary tumors should be considered.

【 授权许可】

   
2013 Tamai et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

【 参考文献 】

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