Gout with auricular tophi following anti-tuberculosis treatment: a case report

BMC Research Notes

Shih-Hung Huang¹  Ying-Chieh Hsu²  Pa-Chun Wang³  Hsin-Jen Chang⁴ 

[1] Department of Pathology, Cathay General Hospital, Taipei, Taiwan;Department of Otolaryngology, Head and Neck Surgery, Cathay General Hospital, Taipei, Taiwan;School of Public Health, China Medical University, Taichung, Taiwan;School of Medicine, Fu Jen Catholic University, Taipei, Taiwan

关键词: Auricle;    Tophus;   

Others  :  1140690
DOI  :  10.1186/1756-0500-6-480

 received in 2012-09-26, accepted in 2013-11-15,  发布年份 2013

【 摘 要 】

Background

Auricular tophi are firm deposits of monosodium urate in crystal form, which may slowly develop in subcutaneous tissue of the ear. Ear is not usual locations for gout tophi, but when this growth does occur, helix and the antihelix are common sites.

Case presentation

We present a 64-year-old man who had multiple painless nodules over bilateral helix. An excisional biopsy was performed. Hematoxylin-eosin staining of biopsy specimens revealed a proteinaceous matrix that surrounded dissolved crystals, consistent with gout tophi. Bilateral auricular tophi are not common and may resemble a number of other diseases including squamous cell carcinomas, Kaposi’s sarcoma, epidermal and dermoid cysts, rheumatoid nodules. Biopsy should be performed to rule out malignancy.

Conclusions

Tophi of the auricle are usually asymptomatic but can become inflamed and occasionally ulcerate through the overlying skin. Chronic tophaceous gout is treated with dietary control and medication. Surgical excision is performed under local anesthetic if symptoms progression or cosmetically deformity is concerned.

【 授权许可】

   
2013 Chang et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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【 参考文献 】

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