Disseminated Aspergillus flavus following septic arthritis in an immunocompetent patient: a case report

BMC Research Notes

Devajit Nath¹  Shah Alam Khan²  Kavin Khatri²  Vivek Tiwari² 

[1] Department of Pathology, All India Institute of Medical Sciences, New Delhi, India;Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi 110029, India

关键词: Tuberculosis;    Knee;    Septic arthritis;    Immunocompetence;    Disseminated;    Aspergillus flavus;    Aspergillosis;   

Others  :  1127297
DOI  :  10.1186/1756-0500-7-709

 received in 2014-06-24, accepted in 2014-09-23,  发布年份 2014

【 摘 要 】

Background

Aspergillosis is a rare cause of osteomyelitis and septic arthritis. Aspergillus osteomyelitis is a debilitating infection affecting both immunocompromised and immunocompetent patients. It is associated with a high incidence of morbidity and mortality. Infection with Aspergillus flavus species in the knee has been very rarely seen in the past.

Case presentation

We present a case of septic arthritis of the knee in an Indian patient secondary to infection with Aspergillus flavus, which was earlier managed as a case of tuberculosis based on the endemicity of the condition, later leading to disseminated aspergillosis. There was no clinical feature or investigation suggesting immunocompromised state. Following knee arthrotomy, Aspergillus flavus was isolated and patient was subsequently managed with antifungals leading to recovery after three months.

Conclusions

Disseminated aspergillosis can mimic tuberculosis both clinically and radiologically. Though fungal infections affect joints rarely but they must always be ruled out to avoid later complications.

【 授权许可】

   
2014 Tiwari et al.; licensee BioMed Central Ltd.

【 图 表 】

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