BMC Infectious Diseases | |
Babesia microti: an unusual travel-related disease | |
Nicolas Schleinitz2  Jean-Robert Harlé2  Renaud Piarroux3  Bernard Carcy1  Emmanuelle Bernit2  Benoit Faucher3  Yael Berda-Haddad4  Mikael Ebbo2  Elodie Poisnel2  | |
[1] Laboratoire de Biologie Cellulaire et Moléculaire Université Montpellier I Faculté de Pharmacie, 15 Avenue Charles Flahault, Montpellier Cedex 5, 134093, France;Service de médecine interne, AP-HM, Aix-Marseille Université, Marseille cedex 5, 13385, France;Laboratoire de Parasitologie, AP-HM, Aix-Marseille Université, Marseille cedex 5, 13385, France;Laboratoire d’hématologie, AP-HM, Aix-Marseille Université, Marseille cedex 5, 13385, France | |
关键词: Travel-related diseases; Hemophagocytosis; Babesia microti; Babesiosis; | |
Others : 1171027 DOI : 10.1186/1471-2334-13-99 |
|
received in 2012-06-22, accepted in 2013-02-18, 发布年份 2013 | |
【 摘 要 】
Background
Human babesiosis is a rare tick-borne infectious disease. The clinical presentation ranges from an asymptomatic form to a life threatening infection with severe hemolysis. Human babesiosis due to Babesia microti is the most common and is endemic in North America.
Case presentation
We report a European patient with severe pancytopenia and reactive hemophagocytosis related to a Babesia microti infection. Babesia infection was acquired during a travel in the USA.
Conclusion
Babesiosis should be considered in patients who traveled in endemic areas, especially North America for the most common agent Babesia microti.
【 授权许可】
2013 Poisnel et al; licensee BioMed Central Ltd.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
20150418025608920.pdf | 386KB | download | |
Figure 2. | 15KB | Image | download |
Figure 1. | 82KB | Image | download |
【 图 表 】
Figure 1.
Figure 2.
【 参考文献 】
- [1]Western KA, Benson GD, Gleason NN, Healy GR, Schultz MG: Babesiosis in a Massachusetts resident. N Engl J Med 1970, 283:854-856.
- [2]Vannier E, Krause PJ: Human babesiosis. N Engl J Med 2012, 366:2397-2407.
- [3]Herwaldt BL, Linden JV, Young C, Olkowska D, Wilson M: Transfusion-Associated Babesiosis in the United States: A Description of Cases. Ann Intern Med 2011, 155:509-519.
- [4]Olmeda AS, Armstrong PM, Rosenthal BM, Valladares B, del Castillo A, de Armas F, Miguelez M, González A, Rodríguez Rodríguez JA, Spielman A, Telford SR 3rd: A subtropical case of human babesiosis. Acta Trop 1997, 67:229-234.
- [5]Isaäcson M: Airport malaria: a review. Bull World Health Organ 1989, 67:737-743.
- [6]Kuwayama DP, Briones RJ: Spontaneous splenic rupture caused by Babesia microti infection. Clin Infect Dis 2008, 46(9):e92-e95.
- [7]Rouphael NG, Talati NJ, Vaughan C, Cunningham K, Moreira R, Gould C: Infections associated with haemophagocytic syndrome. Lancet Infect Dis 2007, 7:814-822.
- [8]Auerbach M, Haubenstock A, Soloman G: Systemic babesiosis. Another cause of the hemophagocytic syndrome. Am J Med 1986, 80:301-303.
- [9]Weiss LM: Babesiosis in humans: a treatment review. Expert Opin Pharmacother 2002, 3(8):1109-1115. Changer