An outbreak of acute norovirus gastroenteritis in a boarding school in Shanghai: a retrospective cohort study

BMC Public Health

Qiao Sun²  Wenqin Wang²  Yong Wang²  Hongmei Xu¹  Lifeng Pan²  Hong Zhang¹  Linying Zhu²  Yi Fei²  Weiping Zhu¹  Yifei Fu²  Caoyi Xue¹ 

[1] Department of Infectious Disease, Pudong District Center for Disease Control and Prevention, Shanghai, China;Research Base of Key Laboratory of Surveillance and Early warning on Infectious Disease in China CDC, Shanghai Pudong District Center for Disease Control and Prevention, 3039 Zhangyang Road, Shanghai 200136, China

关键词: Asymptomatic food handler;    Outbreak;    Acute gastroenteritis;    Norovirus;   

Others  :  1126059
DOI  :  10.1186/1471-2458-14-1092

 received in 2014-04-25, accepted in 2014-10-13,  发布年份 2014

【 摘 要 】

Background

More than 200 students and teachers at a boarding school in Shanghai developed acute gastroenteritis in December, 2012. The transmission mode remained largely unknown. An immediate epidemiological investigation was conducted to identify it.

Methods

Using a retrospective cohort design, we investigated demographic characteristics, school environment, and previous contacts with people who had diarrhea and/or vomiting, drinking water conditions, recalls of food consumption in the school cafeteria, hand-washing habits and eating habits. Rectal swabs of the new cases and food handlers as well as water and food samples were collected to test potential bacteria and viruses. Norovirus was detected by real-time reverse transcription-polymerase chain reaction (RT-PCR).

Results

A total of 278 cases developed gastrointestinal symptoms in this outbreak, and the overall attack rate was 13.9%. The main symptoms included vomiting (50.0%), abdominal cramps (40.3%), nausea (27.0%), diarrhea (6.8%) and fever (6.8%). Twenty rectal swab samples were detected as Norovirus–positive, including 11 from student cases and 9 from asymptomatic food handlers (non-cases). Among environmental surface samples from the kitchen, 8 samples were also detected as Norovirus-positive. The genotypes of viral strains were the same (GII) in patients, asymptomatic food handlers and environmental surfaces. Other samples, including rectal swabs, water samples and food samples were negative for any bacteria and other tested viruses. Asymptomatic food handlers may have contaminated the cooked food during the food preparation.

Conclusion

The study detected that the outbreak was caused by Norovirus and should be controlled by thorough disinfection and excluding asymptomatic food handlers from food preparation. Early identification of the predominant mode of transmission in this outbreak was necessary to prevent new cases. Furthermore, good hygiene practices such as regular hand washing and efficient daily disinfection should be promoted to prevent such infection and outbreaks.

【 授权许可】

   
2014 Xue et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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