Cardiovascular magnetic resonance assessment of the aortic valve stenosis: an in vivo and ex vivo study

BMC Medical Imaging

Behrus Djavidani³  Andreas Luchner¹  Franz-Xaver Schmid²  Kurt Debl¹  Stefan Buchner¹ 

[1] Klinik und Poliklinik für Innere Medizin II, Universitätsklinikum Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg, 93042, Germany;Klinik und Poliklinik für Herz-, Thorax- und herznahe Gefäßchirurgie, Universitätsklinikum Regensburg, Regensburg, Germany;Institut für Röntgendiagnostik, Universitätsklinikum Regensburg, Regensburg, Germany

关键词: Anatomy;    Magnetic resonance imaging;    Aortic stenosis;    Aortic valve;   

Others  :  1222826
DOI  :  10.1186/s12880-015-0076-x

 received in 2015-03-23, accepted in 2015-08-11,  发布年份 2015

【 摘 要 】

Background

Aortic valve area (AVA) estimation in patients with aortic stenosis may be obtained using several methods. This study was undertaken to verify the cardiovascular magnetic resonance (CMR) planimetry of aortic stenosis by comparing the findings with invasive catheterization, transthoracic (TTE) as well as tranesophageal echocardiography (TEE) and anatomic CMR examination of autopsy specimens.

Methods

Our study was performed in eight patients with aortic valve stenosis. Aortic stenosis was determined by TTE and TEE as well as catheterization and CMR. Especially, after aortic valve replacement, the explanted aortic valves were examined again with CMR ex vivo model.

Results

The mean AVA determined in vivo by CMR was 0.75 ± 0.09 cm ²and ex vivo by CMR was 0.65 ± 0.09 cm ²and was closely correlated (r = 0.91, p < 0.001). The mean absolute difference between AVA derived by CMR ex vivo and in vivo was −0.10 ± 0.04 cm ² . The mean AVA using TTE was 0.69 ± 0.07 with a significant correlation between CMR ex vivo (r = 0.85, p < 0.007) and CMR in vivo (r = 0.86, p < 0.008). CMR ex vivo and in vivo had no significant correlation with AVA using Gorlin formula by invasive catheterization or using planimetry by TEE.

Conclusion

In this small study using an ex vivo aortic valve stenosis model, the aortic valve area can be reliably planimetered by CMR in vivo and ex vivo with a well correlation between geometric AVA by CMR and the effective AVA calculated by TTE.

【 授权许可】

   
2015 Buchner et al.

【 图 表 】

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