Cardiovascular magnetic resonance assessment of the aortic valve stenosis: an in vivo and ex vivo study

BMC Medical Imaging

Research Article

Behrus Djavidani¹  Franz-Xaver Schmid²  Stefan Buchner³  Kurt Debl³  Andreas Luchner³ 

[1] Institut für Röntgendiagnostik, Universitätsklinikum Regensburg, Regensburg, Germany;Klinik und Poliklinik für Herz-, Thorax- und herznahe Gefäßchirurgie, Universitätsklinikum Regensburg, Regensburg, Germany;Klinik und Poliklinik für Innere Medizin II, Universitätsklinikum Regensburg, Franz-Josef-Strauss-Allee 11, 93042, Regensburg, Germany;

关键词: Aortic valve;    Aortic stenosis;    Magnetic resonance imaging;    Anatomy;   

DOI  :  10.1186/s12880-015-0076-x

 received in 2015-03-23, accepted in 2015-08-11,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundAortic valve area (AVA) estimation in patients with aortic stenosis may be obtained using several methods. This study was undertaken to verify the cardiovascular magnetic resonance (CMR) planimetry of aortic stenosis by comparing the findings with invasive catheterization, transthoracic (TTE) as well as tranesophageal echocardiography (TEE) and anatomic CMR examination of autopsy specimens.MethodsOur study was performed in eight patients with aortic valve stenosis. Aortic stenosis was determined by TTE and TEE as well as catheterization and CMR. Especially, after aortic valve replacement, the explanted aortic valves were examined again with CMR ex vivo model.ResultsThe mean AVA determined in vivo by CMR was 0.75 ± 0.09 cm2 and ex vivo by CMR was 0.65 ± 0.09 cm2 and was closely correlated (r = 0.91, p < 0.001). The mean absolute difference between AVA derived by CMR ex vivo and in vivo was −0.10 ± 0.04 cm2. The mean AVA using TTE was 0.69 ± 0.07 with a significant correlation between CMR ex vivo (r = 0.85, p < 0.007) and CMR in vivo (r = 0.86, p < 0.008). CMR ex vivo and in vivo had no significant correlation with AVA using Gorlin formula by invasive catheterization or using planimetry by TEE.ConclusionIn this small study using an ex vivo aortic valve stenosis model, the aortic valve area can be reliably planimetered by CMR in vivo and ex vivo with a well correlation between geometric AVA by CMR and the effective AVA calculated by TTE.

【 授权许可】

CC BY   
© Buchner et al. 2015