期刊论文详细信息
BMC Public Health
Sitting time and health outcomes among Mexican origin adults: obesity as a mediator
Laura M Koehly2  Melissa L Bondy5  Larkin L Strong1  Anna V Wilkinson3  Hendrik D de Heer4 
[1] Department of Health Disparities, The University of Texas MD Anderson Cancer Center, Houston, TX, USA;National Human Genome Research Institute, Social and Behavioral Research Branch, Bethesda, MD, USA;Michael & Susan Dell Center for Healthy Living, The University of Texas School of Public Health Austin Regional Campus, Austin, TX, USA;Department of Physical Therapy and Athletic Training, Northern Arizona University, 208 E Pine Knoll Dr. Bldg. 66, Rm. 112, PO Box 15105, Flagstaff 86011, AZ, USA;Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA
关键词: Hispanic;    Hypertension;    Obesity;    Diabetes;    Sitting time;   
Others  :  1162941
DOI  :  10.1186/1471-2458-12-896
 received in 2012-01-06, accepted in 2012-10-16,  发布年份 2012
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【 摘 要 】

Background

Sitting time and sedentary behaviors have been associated with adverse health outcomes including obesity, diabetes and cardiovascular disease (CVD) within non- Hispanic White populations. Similar associations have not been described within Hispanic populations despite their high CVD risk profile. This study aimed to assess the association between sitting time and obesity, self-reported diagnosed diabetes, hypertension and high cholesterol among a large cohort (N=11,268) of Mexican origin adults and to assess whether obesity mediated these associations.

Methods

Using a cross-sectional design, data collected between 2004 and 2010 were analyzed in late 2010. Regression analyses evaluated associations between self-reported daily sitting hours and disease outcomes, controlling for demographics, employment status, family disease history, and light, moderate and strenuous physical activity.

Results

Participants were mostly female (81.1%) Mexican origin adults. Sitting time was associated with increased odds of being obese, having diabetes and having hypertension, but not high cholesterol. Adjusted odds ratios of participants who reported sitting > 4 hours/day compared to those sitting 1-2 hours/day were for obesity OR=1.55 (95% CI 1.39, 1.73), p<.001, for diabetes OR=1.29 (95% CI, 1.09, 1.52), p=.003, for hypertension OR=1.17 (95% CI, 1.01, 1.37), p=.041. Associations controlled for physical activity and employment status. Effects on hypertension and diabetes were mediated by obesity.

Conclusions

Sitting time was significantly associated with detrimental health outcomes, independent of physical activity. Obesity mediated these relationships for diabetes and hypertension. Future research should assess whether interventions addressing sitting time are feasible and effective among Mexican origin populations.

【 授权许可】

   
2012 de Heer et al.; licensee BioMed Central Ltd.

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【 参考文献 】
  • [1]Matthews CE, Chen KY, Freedson PS, et al.: Amount of time spent in sedentary behaviors in the United States, 2003-2004. Am J Epidemiol 2008, 167(7):875-881.
  • [2]Hu FB, Li TY, Colditz GA, et al.: Television watching and other sedentary behaviors in relation to risk of obesity and type 2 diabetes mellitus in women. JAMA 2003, 289:1785-1791.
  • [3]Hu FB, Leitzmann MF, Stampfer MJ, et al.: Physical activity and TV watching in relation to risk for type 2 diabetes mellitus in men. Arch Intern Med 2001, 161:1542-1548.
  • [4]Gao X, Nelson ME, Tucker KL: Television viewing is associated with prevalence of metabolic syndrome in Hispanic elders. Diab Care 2007, 30:694-700.
  • [5]Healy GN, Dunstan DW, Salmon J, et al.: Objectively measured light-intensity physical activity is independently associated with 2-h plasma glucose. Diab Care 2007, 28(1):1384-1389.
  • [6]Dunstan DW, Salmon J, Healy GN, et al.: The AusDiab Steering Committee: Association of TV viewing with fasting and 2-h postchallenge plasma glucose levels in adults without diagnosed diabetes. Diab Care 2007, 30:516-522.
  • [7]Healy GN, Wijndaele K, Dunstan DW, et al.: Objectively measured sedentary time, physical activity, and metabolic risk: the Australian Diabetes, Obesity and Lifestyle Study (AusDiab). Diab Care 2008, 31:369-371.
  • [8]Thorp AA, Healy GN, Owen N, et al.: Deleterious associations of sitting time and television viewing time with cardiometabolic risk biomarkers: Australian Diabetes, Obesity and Lifestyle (AusDiab) study 2004-2005. Diab Care 2010, 33:327-334.
  • [9]Jakes RW, Day NE, Khaw KT, et al.: Television viewing and low participation in vigorous recreation are independently associated with obesity and markers of cardiovascular disease risk: EPIC-Norfolk population-based study. Eur J Clin Nutr 2003, 57:1089-1096.
  • [10]Dunstan DW, Salmon J, Owen N, et al.: Associations of TV viewing and physical activity with the metabolic syndrome in Australian adults. Diabetologia 2005, 48:2254-2261.
  • [11]Healy GN, Dunstan DW, Salmon J, et al.: Television time and continuous metabolic risk in physically active adults. Med Sci Sports Exec 2008, 40:639-645.
  • [12]Dunstan DW, Barr ELM, Healy GN, et al.: Television viewing time and mortality: The Australian Diabetes, Obesity and Lifestyle Study (AusDiab). Circulation 2010, 121:384-391.
  • [13]Dunstan DW, Salmon J, Owen N, et al.: Physical activity and television viewing in relation to risk of undiagnosed abnormal glucose metabolism in adults. Diab Care 2004, 27(11):2603-2609.
  • [14]Owen N, Healy GN, Matthews CE, et al.: Too much sitting: the population health science of sedentary behavior. Exerc Sport Sci Rev 2010, 38(3):105-113.
  • [15]Owen N, Bauman A, Brown W: Too much sitting: a novel and important predictor of chronic disease risk? Br J Sports Med 2009, 43(2):81.
  • [16]Fung TT, Hu FB, Yu J, et al.: Leisure-time physical activity, TV watching, and plasma biomarkers of obesity and cardiovascular disease risk. Am J Epidemiol 2000, 152:1171-1178.
  • [17]van Uffelen JGZ, Wong J, Chau JY, et al.: Occupational sitting and health risks: a systematic review. Am J Prev Med 2010, 39(4):379-388.
  • [18]Owen N, Leslie E, Salmon J, et al.: Environmental determinants of physical activity and sedentary behaviour. Exerc Sport Sci Rev 2000, 28(4):165-170.
  • [19]Levine JA, Eberhardt NL, Jensen MD: Role of non- exercise activity thermogenesis in resistance to fat gain in humans. Science 1999, 283:212-214.
  • [20]Mummery WK, Schofield GM, Steele R, et al.: Occupational sitting time and overweight and obesity in Australian workers. Am J Prev Med 2005, 29(2):91-97.
  • [21]Hamilton MT, Hamilton DG, Zderic TW: Role of low energy expenditure and sitting in obesity, metabolic syndrome, type 2 diabetes, and cardiovascular disease. Diabetes 2007, 56(11):2655-2667.
  • [22]Katzmarzyk PT, Church TS, Craig CL, et al.: Sitting time and mortality from all causes, cardiovascular disease, and cancer. Med Sci Sport Exerc 2009, 41(5):998-1005.
  • [23]Brown WJ, Williams L, Ford JH, et al.: Identifying the energy gap: magnitude and determinants of 5-year weight gain in midage women. Obes Res 2005, 13:1431-1441.
  • [24]Proper KI, Cerin E, Brown WJ, et al.: Sitting time and socio-economic differences in overweight and obesity. Int J Obesity 2007, 31(1):169-176.
  • [25]Hamilton MT, Healy GN, Dunstan DW, et al.: Too little exercise and too much sitting: inactivity physiology and the need for new recommendations on sedentary behavior. Curr Cardiovasc Risk Rep 2008, 2:292-298.
  • [26]Stamatakis E, Hamer M, Dunstan DW: Screen-Based Entertainment Time, All-Cause Mortality, and Cardiovascular Events. J Am Coll of Cardiol 2011, 57:292-299.
  • [27]United States Bureau of the Census: The Hispanic Population. 2010. Available at: http://www.census.gov/prod/cen2010/briefs/c2010br-04.pdf webcite
  • [28]Centers for Disease Control and Prevention (CDC): Differences in Prevalence of Obesity Among Black, White, and Hispanic Adults - United States, 2006- 2008. MMWR 2009, 58(27):740-744.
  • [29]Centers for Disease Control and Prevention: National diabetes fact sheet: national estimates and general information on diabetes and pre-diabetes in the United States, 2011. Atlanta: Department of Health and Human Services, Centers for Disease Control and Prevention; 2011.
  • [30]Wilkinson AV, Spitz MR, Strom SS, et al.: Effects of nativity, age at migration, and acculturation on smoking among adult Houston residents of Mexican descent. Am J Public Health 2005, 95:1043-1049.
  • [31]The University of Texas MD Anderson Cancer Center: Tobacco Settlement Proceeds Program. 2009. Available from: http://www.mdanderson.org/about-us/university-of-texas-system-reports/files/tobacco-planned-expenditures-fy-2009.pdf webcite
  • [32]Rogot E, Sorlie PD, Johnson NJ: Life expectancy by employment status, income, and education in the National Longitudinal Mortality Study. Public Health Rep 1992, 107(4):457-461.
  • [33]Mai PL, Sullivan-Halley J, Ursin G, et al.: Physical activity and colon cancer risk among women in the California Teachers Study. Cancer Epidemiol Biomarkers Prev 2007, 16:517-525.
  • [34]Ainsworth B, Haskell WL, White MC, et al.: Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc 2000, 32(suppl):S498-S504.
  • [35]Herr NR: Mediation with dichotomous outcomes. 2011. Retrieved March 15th, 2011 from: http://nrherr.bol.ucla.edu/Mediation/logmed.html webcite
  • [36]Sobel ME: Asymptotic confidence intervals for indirect effects in structural equation models. In Sociological Methodology. Edited by Leinhardt S. San Fransisco: Jossey-Bass; 1982:290-312.
  • [37]Baron RM, Kenny DA: The moderator–mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations. J Pers Soc Psych 1986, 51:1173-1182.
  • [38]Zderic TW, Hamilton MT: Physical inactivity amplifies the sensitivity of skeletal muscle to the lipid-induced downregulation of lipoprotein lipase activity. J Appl Physiol 2006, 100:249-257.
  • [39]Bowman SA: Television-viewing characteristics of adults: correlations to eating practices and overweight and health status. Prev Chr Dis 2006, 3(2):1-11.
  • [40]Johannsen DL, Welk G, Sharp RL, et al.: Differences in daily energy expenditure in lean and obese women: the role of posture allocation. Obesity 2008, 16:34-39.
  • [41]Healy GN, Clark BK, Winkler EAH, et al.: measurement of adults sedentary time in population-based studies. Am J Prev Med 2011, 41(2):216-227.
  • [42]Janssen I, Katzmarzyk P, Ross R: Waist circumference and not body mass index explains obesity-related health risk. Am J Clin Nutr 2004, 79:379-84.
  • [43]Healy GN, Dunstan DW, Salmon J, et al.: Breaks in sedentary time: beneficial associations with metabolic risk. Diab Care 2008, 31:661-666.
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