Biventricular thrombi in dilated cardiomyopathy in a patient with human immunodeficiency virus infection: a case report

BMC Research Notes

Alain Menanga²  Jerome Boombhi²  Sandrine Dikosso Edie²  Engelbert Bain Luchuo¹  Liliane Mfeukeu Kuate³  Clovis Nkoke² 

[1] Department of Military Health, Ministry of Defense, Yaounde, Cameroon;Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon;Cardiology Unit, Yaounde Central Hospital, Yaounde, Cameroon

关键词: Sub-Saharan Africa;    Biventricular thrombi;    Human immunodeficiency virus;    Dilated cardiomyopathy;   

Others  :  1177862
DOI  :  10.1186/s13104-015-1140-x

 received in 2014-08-22, accepted in 2015-04-22,  发布年份 2015

【 摘 要 】

Background

Sub-Saharan Africa is undergoing epidemiological transition with an increase in the prevalence of cardiovascular diseases that will add to the already devastating burden of infectious diseases such as human immunodeficiency virus infection. Human immunodeficiency virus infection is increasingly being recognized as an important etiological factor for dilated cardiomyopathy with the potential complication of intraventricular thrombus. However, biventricular thrombi are extremely rare. We report on a rare finding of biventricular thrombi in dilated cardiomyopathy in a patient with human immunodeficiency virus infection in Cameroon.

Case presentation

A 52-year old Cameroonian male patient with human immunodeficiency virus infection since 4 years, longstanding heavy alcohol consumption and cigarette smoking presented with gradually worsening shortness of breath, fatigue, persistent dry cough and lower extremity swelling of about two weeks duration. Congestive heart failure was diagnosed. Echocardiography showed left ventricular chamber enlargement with severe left ventricular systolic dysfunction and biventricular thrombi. The thrombi were immobile and regular in configuration, suggesting they were old. He was treated with a conventional heart failure treatment including loop diuretics and angiotensin converting enzyme inhibitors and anticoagulants for the biventricular thrombi. Six months later, a control echocardiography showed a significant decrease in the size of the thrombi. There was no evidence of systemic or pulmonary embolization during follow up.

Conclusion

Dilated cardiomyopathy may be seen in patients with human immunodeficiency virus infection, although other mechanisms needs to be assessed, but the occurrence of biventricular thrombi is rare.

【 授权许可】

   
2015 Nkoke et al.; licensee BioMed Central.

【 图 表 】

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