Evidence of Bos javanicus x Bos indicus hybridization and major QTLs for birth weight in Indonesian Peranakan Ongole cattle

BMC Genetics

Muladno Muladno³  Jakaria Jakaria³  José Fernando Garcia⁴  Tad Stewart Sonstegard¹  Yuri Tani Utsunomiya²  Hartati Hartati⁵ 

[1] ARS-USDA - Agricultural Research Service - United States Department of Agriculture, Animal Genomics and Improvement Laboratory, Beltsville 20705, MD, USA;Faculdade de Ciências Agrárias e Veterinárias, UNESP - Univ Estadual Paulista, Jaboticabal 14884-900, São Paulo, Brazil;Faculty of Animal Science, Bogor Agriculture University, Jln. Agatis kampus IPB Dramaga, Bogor 16680, Indonesia;Faculdade de Medicina Veterinária de Araçatuba, UNESP – Univ Estadual Paulista, Araçatuba 16050-680, São Paulo, Brazil;Beef Cattle Research Station, Indonesian Agency for Agricultural Research and Development, Ministry of Agriculture, Jln. Pahlawan no. 2 Grati, Pasuruan 16784, East Java, Indonesia

关键词: birth weight;    Bos javanicus;    Bos indicus;    Nellore;    Peranakan Ongole;   

Others  :  1218919
DOI  :  10.1186/s12863-015-0229-5

 received in 2015-04-15, accepted in 2015-06-10,  发布年份 2015

【 摘 要 】

Background

Peranakan Ongole (PO) is a major Indonesian Bos indicus breed that derives from animals imported from India in the late 19 ^thcentury. Early imports were followed by hybridization with the Bos javanicus subspecies of cattle. Here, we used genomic data to partition the ancestry components of PO cattle and map loci implicated in birth weight.

Results

We found that B. javanicus contributes about 6-7 % to the average breed composition of PO cattle. Only two nearly fixed B. javanicus haplotypes were identified, suggesting that most of the B. javanicus variants are segregating under drift or by the action of balancing selection. The zebu component of the PO genome was estimated to derive from at least two distinct ancestral pools. Additionally, well-known loci underlying body size in other beef cattle breeds, such as the PLAG1 region on chromosome 14, were found to also affect birth weight in PO cattle.

Conclusions

This study is the first attempt to characterize PO at the genome level, and contributes evidence of successful, stabilized B. indicus x B. javanicus hybridization. Additionally, previously described loci implicated in body size in worldwide beef cattle breeds also affect birth weight in PO cattle.

【 授权许可】

   
2015 Hartati et al.

【 图 表 】

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