Chronic recurrent multifocal osteomyelitis manifested as painful clavicular swelling: a case report

BMC Research Notes

Klaus Weckbecker¹  Bernd Sommer²  Markus Bleckwenn¹ 

[1] Department of General Practice and Family Medicine, University Medical Center Friedrich-Wilhelm University Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany;Practice for Radiology and Nuclear Medicine, Am Cura-Krankenhaus, Schülgenstr. 15a, 53604 Bad Honnef, Germany

关键词: Nonbacterial inflammation;    Diagnostic imaging;    Hyperostosis;    Clavicular swelling;    CRMO;    Osteomyelitis;   

Others  :  1125694
DOI  :  10.1186/1756-0500-7-786

 received in 2014-06-15, accepted in 2014-10-17,  发布年份 2014

【 摘 要 】

Background

Chronic recurrent multifocal osteomyelitis is a form of non-bacterial osteomyelitis which occurs primarily in childhood. In some cases painful bone swelling occurs. After a malignancy has been ruled out, antibiotic therapy is often started to treat the osteomyelitis. The course of this benign disease is self-limiting and is not positively affected by the antibiotic therapy.

Case presentation

A 14-year-old German girl from South Africa came to the surgery with painful swelling in the right clavicle. The condition had first appeared two months earlier. The patient was unable to identify a trigger. In addition, the patient exhibited painless swelling in the area of the 5^th metatarsal of the left foot. Chronic recurrent multifocal osteomyelitis was diagnosed based on characteristic clinical symptoms and imaging. Treatment with ibuprofen had caused the symptoms to regress rapidly.

Conclusion

The case demonstrates to general practitioners and other clinicians that a prolonged administration of antibiotics can be prevented by means of a comprehensive diagnostic procedure for possible bacterial osteomyelitis.

【 授权许可】

   
2014 Bleckwenn et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

【 参考文献 】

• [1]Schuster T, Bielek J, Dietz HG, Belohradsky BH: Chronic recurrent multifocal osteomyelitis (CRMO). Eur J Pediatr Surg 1996, 6:45-51.
• [2]Jansson A, Golla A, Schneider K, Jansson V, Belohradsky BH: Die chronisch rezidivierende multifokale Osteomyelitis (CRMO) Übersicht und erste Befunde einer genetisch-rheumatologischen Studie. Monatsschr Kinderheilkd 2002, 150:477-489.
• [3]Jansson A, Golla A, Plewig G, Meindl A, Belohradsky BH: Chronisch rezidivierende multifokale Osteomyelitis und andere nichtbakterielle Osteitiden - Klinik, Diagnostik, Therapie, Prognose und genetische Untersuchungen. Dtsch Arztebl 2004, 101:A584-A589.
• [4]Schilling F, Both S, Coerdt W, Lausch E, Oberholzer K, Zepp F: Die Multifokale rekurrierende Periostitis des Kindes- und Jugendalters (MRP): Übersicht und Kasuistik einer subakuten multifokalen Osteo-Periostitis. Osteologie 2001, 10:118-129.
• [5]Schultz C, Jonas S, Schnekenburger FG, Russlies M, Kruse K, Bucsky P: Chronisch rezidivierende multifokale Osteomyelitis. Monatsschr Kinderheilkd 1997, 145:1186-1193.