The risk to import ESBL-producing Enterobacteriaceae and Staphylococcus aureus through chicken meat trade in Gabon

BMC Microbiology

Alexander Mellmann²  Georg Peters¹  Peter G Kremsner⁵  Saadou Issifou⁵  Karsten Becker¹  Robin Köck²  Martin P Grobusch⁴  Lisa Frielinghaus³  Abraham S Alabi⁵  Frieder Schaumburg³ 

[1] Institute of Medical Microbiology, University Hospital Münster, Domagkstr. 10, Münster, 48149, Germany;Institute of Hygiene, University Hospital Münster, Münster, Germany;Centre de Recherches Médicales de Lambaréné, Albert Schweitzer Hospital, Lambaréné, Gabon;Department of Infectious Diseases, Division of Internal Medicine, Center for Tropical Medicine and Travel Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands;Institut für Tropenmedizin, Eberhard Karls Universität and Deutsches Zentrum für Infektionsforschung, Tübingen, Deutschland

关键词: Africa;    Trade;    Chicken meat;    Antimicrobial resistance;    Escherichia coli;    Staphylococcus aureus;   

Others  :  1137729
DOI  :  10.1186/s12866-014-0286-3

 received in 2014-08-05, accepted in 2014-11-06,  发布年份 2014

【 摘 要 】

Background

A main export market for chicken meat from industrialized countries is sub-Saharan Africa. We hypothesized that antibiotic resistant bacteria could be exported to developing countries through chicken meat trade. The objective was to investigate the occurrence and molecular types of ESBL-producing Enterobacteriaceae and Staphylococcus aureus in chicken meat in Gabon and to assess their dissemination among humans.

Results

Frozen chicken meat samples imported from industrialized countries to Gabon (n = 151) were screened for ESBL-producing Enterobacteriaceae and S. aureus. Genotypes and resistance genes (SHV, TEM, CTX-M, CMY-2) of isolates from meat were compared with isolates derived from humans.

The contamination rate per chicken part (i. e. leg, wing) with ESBL-producing Escherichia coli (ESBL E. coli, no other ESBL-producing Enterobacteriaceae were found) and S. aureus was 23% and 3%, respectively. The beta-lactamase CTX-M 1 was predominant in ESBL E. coli from meat samples but was not found in isolates from cases of human colonization or infection. S. aureus belonging to spa type t002 (multilocus sequence type ST5) were found both in chicken meat and humans.

Conclusion

There is a risk to import ESBL E. coli to Gabon but molecular differences between isolates from humans and chicken meat argue against a further dissemination. No MRSA isolate was detected in imported chicken meat.

【 授权许可】

   
2014 Schaumburg et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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