A Rome III survey of functional dyspepsia among the ethnic Malays in a primary care setting

BMC Gastroenterology

Andrew Seng Boon Chua²  Juwita Shaaban¹  Noorhayati Mohd Noor¹  Norwati Daud¹  Nazri Mustaffa³  Noriza Wahab¹  Yeong Yeh Lee³ 

[1] Department of Family Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia;Gastro Centre Ipoh, 31 Lebuh Raya Raman Ipoh, Ipoh Garden South, 31400, Ipoh, Perak, Malaysia;Department of Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia

关键词: Psychosocial alarm;    Marriage;    Females;    Rome III;    Malays;    Functional dyspepsia;   

Others  :  857987
DOI  :  10.1186/1471-230X-13-84

 received in 2012-08-31, accepted in 2013-05-10,  发布年份 2013

【 摘 要 】

Backgrounds

The study aimed to survey for FD in a primary care setting in a population known to have an extremely low prevalence of Helicobacter pylori (H. pylori) infection, with the hypothesis that in such a population, dyspepsia should have been relatively less common.

Methods

The Rome III FD Diagnostic Questionnaire was translated into the Malay language and later tested for reliability. A prospective cross-sectional survey was then performed involving 160 Malay patients attending primary care clinic after informed consent. Patients positive for symptoms of FD were subjected to upper endoscopy and exclusion of H. pylori infection. Univariable and multivariable analyses were used to test for associated risk factors.

Results

The back-translated questionnaire was similar to the original English version and was reliable (Cronbach Alpha-coefficient 0.85). Of the 160 surveyed subjects, 19 of them (11.9%) had symptoms of FD. With exclusion of erosive diseases (3/160 or 1.9%) from endoscopy, 16 subjects or 10% had FD. None of the 19 subjects were positive for H. pylori infection. Epigastric pain syndrome was present in 11/16 (68.8%) and the rest, overlap with postprandial distress syndrome. With multivariable analysis, a married status (OR = 8.1; 95% CI 1.0-36.5) and positive psychosocial alarm symptoms (OR = 3.8; 95% CI 1.0-14.0) were associated with FD. Of those married subjects, females were more likely to have FD and psychosocial symptoms than men (6.3% vs. 1.9%), P = 0.04.

Conclusions

FD was more common than one had expected among Malays attending primary care clinic in an area with low prevalence of H. pylori.

【 授权许可】

   
2013 Lee et al.; licensee BioMed Central Ltd.

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